PhD Scientific Days 2017

Poster Presentation: Cardiovascular

P67: Determining left and right ventricular cardiac magnetic resonance parameters using threshold-based trabecula quantification method by three independent observers

Előadó neve

Dr. Csecs, Ibolya

Előadó munkahelye

Semmelweis University Heart and Vascular Center

Előadó telefonszáma

+36206632859

Előadó e-mail címe

ibolyacsecs@gmail.com

Az előadás címe

Determining left and right ventricular cardiac magnetic resonance parameters using threshold-based trabecula quantification method by three independent observers

Szerző(k) neve és munkahelye

Ibolya Csecs, Csilla Czimbalmos, Ferenc I Suhai, Róbert Mikle, Zsófia Dohy, Beáta Horváth, Attila Tóth, Béla Merkely, Hajnalka Vágó
Heart and Vascular Center of the Semmelweis University, Budapest

Szekció

Poster Presentation: Cardiovascular

Data of the presenter

Doctoral School: Basic Medicine
Program: Cardiovascular Disorders: Physiology and Medicine of Ischaemic Circulatory Diseases
Supervisor: Hajnalka Vágó
E-mail address: ibolyacsecs@gmail.com

Text of the abstract

While cardiovascular magnetic resonance (CMR) is the gold standard method to evaluate left and right ventricular functions, volumes and masses, there is no widely accepted method for the quantitative analysis of trabeculae (TrM) and papillary muscles (PM). During the past few years besides conventional segmentation algorithms, threshold-based (TB) quantification options also became available.

Our aims were 1) to evaluate left (LV) and right ventricular (RV) CMR parameters by conventional and threshold-based quantification methods 2) measure the papillary and trabecular masses in both ventricles 3) compare CMR parameters determining by three independent observers.

At our Clinic 60 healthy volunteer (mean age 30±5 years, 30 male) underwent CMR scan performed on a 1.5T Philips Achieva MR machine. On short-axis cine images endo- and epicardial contours were detected by three independent observers with different level of experience (Level1=75, Level2>800, Level3>5000 original CMR cases). Using conventional and threshold-based methods (Medis7.6QMass) we measured LV and RV ejection fractions, volumes and masses, threshold-based method also enables the quantification of TrM. Using the same contours we compared the impact of threshold-based option at all readers. Expert observer also contoured the papillary muscles manually.

Comparing the two methods significant difference were detected for each investigated parameters regardless of experience level (L1,L2,L3 P<0.0001). Quantifying the PM resulted significant changes in LV volumetric and mass parameters (P<0.0001). TrM was higher than PM (31.4% vs 5.5% of LVM P<0.0001). Interobserver agreement was excellent for volumetric parameters with both methods (intraclass correlation coefficient (ICC) of LVEDVi 0.978 and 0.969, RVEDVi 0.947 and 0.959)), measuring LV and RV masses threshold-based quantification seems to be more reliable (ICC of LVMi 0.867 and 0.936, RVMi 0.754 and 0.920).

The quantitative analysis of papillary muscles and myocardial trabeculation could fundamentally alter the normal LV and RV parameters. Threshold-based algorithm could be a consistent method to assess the trabeculae quantitatively.

Azonosító

P67

Kind

Szabad

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

1133

Authors (legacy)

Ibolya Csecs, Csilla Czimbalmos, Ferenc I Suhai, Róbert Mikle, Zsófia Dohy, Beáta Horváth, Attila Tóth, Béla Merkely, Hajnalka Vágó
Heart and Vascular Center of the Semmelweis University, Budapest