PhD Scientific Days 2018

Oral presentations: Neurosciences

How EMF exposure leads to passive exercise?

Előadó neve

Téglás, Tímea

Előadó munkahelye

University of Physical Education

Előadó telefonszáma

+36703862804

Előadó e-mail címe

timea.teglas87@gmail.com

Az előadás címe

How EMF exposure leads to passive exercise?

Szerző(k) neve és munkahelye

T. Teglas1, G. Dornyei2, K. Bretz1, Cs. Nyakas1,2
1 University of Physical Education, Budapest, Hungary
2 Semmelweis University, Budapest, Hungary

Bemutatás módja

Szóbeli

Szekció

Oral presentations: Neurosciences

Language of the presentation

Hungarian

Témacsoport

neurosciences

Összefoglaló szövege

Introduction and aims. During advanced aging passive exercise (PE) is becoming a valuable therapeutic intervention to improve physical and mental performances. In the present study chronic PE (electromagnetic field stimulation, EMF-S) was introduced to rats reaching the senescent age of 32 months in order to develop a translational model for supporting healthy aging, attenuating cognitive decline and to clarify the mechanism of action of EMF-S on brain and muscle tissues during advanced aging.

Methods. Male Wistar rats were treated with EMF-S for six weeks, 3 times per week, 24 min per sessions prior to the age of 32 months. The doses of stimulation were: 45, 95 and 1250µT. Psychomotility (horizontal and vertical ambulation in novel environment) was estimated in open field (OF), the attention ability in novel object recognition (NOR) test, and spatial learning, reference and working memories, in Morris water maze (MWM) tests.

Results. OF: EMF-S enhanced novelty-induced motility, especially that of vertical type after both the middle and high doses (p<0.05 at both doses). NOR: EMF-S increased attention after middle and high doses (p<0.001 and p<0.01, respectively) reflecting an enhanced attentional capability based on memory enhancement. MWM: passive exercise facilitated the working memory type spatial learning in this test and the highest dose of 1250µT was clearly effective (ANOVA, p=0.024).

Conclusions. The results obtained on cognitive tasks showed that EMF stimulation as PE is effective in senescent age to improve cognitive and psychomotor function in rats. In the age of 32 months in this rodent both of these cognitive functions are rather deteriorated revealed by our earlier studies. The results support the notion that PE may complete dementia prevention program in elderlies. These animal studies can provide options to study the cellular and molecular mechanisms behind this treatment helping human interventions.
Supported by OTKA Grant K116511 in Hungary.

Data of the presenter

Doctoral School: Sportsciences
Program: Physical training, regulation, metabolism
Supervisor: Csaba Nyakas
E-mail address: nyakas@tf.hu

Kind

Szabad

Status

visszavonva

Accepted presentation method

szóbeli

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

2927

Authors (legacy)

T. Teglas1, G. Dornyei2, K. Bretz1, Cs. Nyakas1,2
1 University of Physical Education, Budapest, Hungary
2 Semmelweis University, Budapest, Hungary