Theoretical and Translational V. Lectures
Sipos, Evelin, MSc
Department of Biophysics and Radiation Biology, Semmelweis University
06303754288
sipos.evelin@med.semmelweis-univ.hu
Characteristic Load-elongation Behavior of Weak Electrospun Fiber Texture
Evelin Sipos, Akos Juhasz, Miklos Zrinyi
Laboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University
Theoretical and Translational V. Lectures
English
Theoretical and Translational Medicine
Molecular Sciences
Electrospun nano- and micro-fiber networks have attracted an intensive research area over the past decades, due to their high mechanical performances and low weight. However the electrospinning technology is well developed, little is known on the deformation mechanism of electrospun fiber networks. For biomedical applications damage accumulation, fraction and nonlinear mechanical behavior are important characteristics of the fibrous materials.
The main purpose of this research is to establish the characteristic load-displacement behavior of weak, planar, randomly oriented fiber bundles.
The fundamental mechanical properties were studied by unidirectional strain-controlled stretching on fibrous electrospun networks prepared from polysuccinimide, which is the anhydrous form of poly(aspartic acid), so the networks are biocompatible and biodegradable, ideal for several biomedical applications like scaffold for cell proliferation and artificial extracellular matrix. 2D randomly oriented fibre mats were prepared using a home-made electrospinning instrument.
The experimental loading curve shows a symmetrical parabolic type dependence at large scale and saw tooth-like forceextension behavior at small scale. The damage formation was quantified by determining the number and the magnitude of abrupt force drops. The experiments evidenced that damage evolution is a consequence of strain induced random events, which may caused by failer and rupture of fibers. Based on the Fiber Bundle Model, the loading force can be directly related to the cumulative probability distribution function of failures, appearing on the loading curve as abrupt force drops during extension. We estimated the cumulative empirical distribution function of rupture force and analyzed them on the basis of Weibull distribution. The shape parameter of distribution proves that, the rupture force of electrospun fiber bundles follows the exponential distribution function.
This experimental technique can provide the initial stiffness as well as to explain load bearing capacity of several synthetic and biological textures that are composed of fibers. It also suggests improved probabilistic approaches to the development of more sophisticated statistical models.
Supervisor: Miklós Zrínyi
E-mail: mikloszrinyi@gmail.com
Szóbeli
Szabad
elfogadva
szóbeli
nem rendelkezett róla
4767
18:00
18:15
Evelin Sipos, Akos Juhasz, Miklos Zrinyi
Laboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University