PhD Scientific Days 2020

Clinical Medicine II. Lectures

The Evaluation of Strain Parameters Using Functional CT Angiography

Előadó neve

Dr. Vattay, Borbála

Előadó munkahelye

Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University

Előadó telefonszáma

06206632491

Előadó e-mail címe

bori.vattay@gmail.com

Az előadás címe

The Evaluation of Strain Parameters Using Functional CT Angiography

Szerző(k) neve és munkahelye

Borbála Vattay1, Bálint Szilveszter1, Anikó Ilona Nagy1, Astrid Apor1, Márton Kolossváry1, Melinda Boussoussou1, Judit Simon1, Bartykowszki Andrea1, Attila Tóth1, Ferenc Imre Suhai1, Béla Merkely1, Pál Maurovich-Horvat1,2
1 Heart and Vascular Center, Semmelweis University, Budapest
2 Medical Imaging Center, Semmelweis University, Budapest

Szekció

Clinical Medicine II. Lectures

Language of the presentation

Hungarian

Section, first choice

Clinical Medicine

Section, second choice

Health Sciences

Összefoglaló szövege

Introduction: Longitudinal strain measured by speckle tracking echocardiography (STE) has emerged as an early sensitive marker of left ventricular (LV) dysfunction. Cardiac CT angiography, due to its high spatial resolution, allows for reliable evaluation of the LV morphology. Moreover, the assessment of myocardial strain became feasible based on functional CT datasets. However, data on myocardial deformation imaging using CT angiography are limited.
Aims: To compare STE and CT derived LV and left atrial (LA) global longitudinal strain (GLS) parameters obtained by using a feature tracking algorithm in patients who underwent transcatheter aortic valve implantation (TAVI).
Method: We enrolled 28 post-TAVI patients (mean age: 78.2 ± 9 .4 years, women: 60.7%) who underwent retrospectively gated cardiac CT angiography and echocardiography on the same day. We reconstructed CT datasets in 10% increments throughout the entire cardiac cycle. LV functional parameters including ejection fraction (EF) and GLS were measured on 2- and 4-chamber views on both CT and echocardiography. In case of global peak reservoir strain (LAGS) measurements were carried out using 2-chamber images with both modalities.
Results: Median LV EF was 58.1 [47.6 - 65.2] % on CT vs. 62.5 [50.3 - 68.3] % on STE. Median LV GLS was 19.9 [14.8-22.4] on CT vs. 19.9 [16.8 - 24.7] on STE. Our results showed strong correlation between CT and STE for the measurement of LV GLS with a mean bias of -1.6. Between the two imaging modalities correlation coefficients were ρ=0.78 and ρ=0.70 for LV GLS and EF, respectively, p<0.05 in both cases. The median LAGS was 19.0 [13.5-27.3] for CT vs. 28.0 [17.5-32.6] for STE. We detected good correlation for LAGS measures with a mean bias of -5.6, inter-modality correlation coefficient was ρ=0.87, p<0.001.
Conclusion: We demonstrated good correlation in quantifying global LV GLS and EF using CT angiography as compared with echocardiography. Moreover, the evaluation atrial strain using CT is feasible and demonstrated good correlation with STE.

Additional Information

Supervisor: Balint Szilveszter
E-mail address: szilveszter.balint@gmail.com

Bemutatás módja

Szóbeli

Kind

Szabad

Status

elfogadva

Accepted presentation method

szóbeli

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

4778

Start

12:20

End

12:35

Authors (legacy)

Borbála Vattay1, Bálint Szilveszter1, Anikó Ilona Nagy1, Astrid Apor1, Márton Kolossváry1, Melinda Boussoussou1, Judit Simon1, Bartykowszki Andrea1, Attila Tóth1, Ferenc Imre Suhai1, Béla Merkely1, Pál Maurovich-Horvat1,2
1 Heart and Vascular Center, Semmelweis University, Budapest
2 Medical Imaging Center, Semmelweis University, Budapest