PhD Scientific Days 2021

CL_I_L: Clinical Medicine I. Lectures

Differences in mitral and tricuspid annular geometry in elite athletes with versus without functional mitral regurgitation: a 3D echocardiographic study

Előadó neve

Dr. Fábián, Alexandra

Előadó munkahelye

Semmelweis University, Doctoral School of Theoretical and Translational Medicine

Előadó telefonszáma

+36209838298

Előadó e-mail címe

f.ala934@gmail.com

Az előadás címe

Differences in mitral and tricuspid annular geometry in elite athletes with versus without functional mitral regurgitation: a 3D echocardiographic study

Szerző(k) neve és munkahelye

Alexandra Fábián1,
1 Semmelweis University, Doctoral School of Theoretical and Translational Medicine

Bemutatás módja

Szóbeli

Szekció

Clinical Medicine I. Lectures

Language of the presentation

Hungarian

Preferred session

Health Sciences

Összefoglaló szövege

Intense exercise exposes the heart to significant hemodynamic demands, resulting in adaptive changes in cardiac morphology and function. Nevertheless, the athletic adaptation of the atrioventricular valves remains to be elucidated. Our study aimed to characterize the geometry of mitral (MA) and tricuspid (TA) annuli in elite athletes using 3-D echocardiography.

Thirty-four athletes presented with functional mitral regurgitation (FMR) were retrospectively identified and compared with 34 athletes without mitral regurgitation (MR) and 34 healthy, sedentary volunteers. 3-D echocardiographic datasets were used to quantify MA and TA geometry and leaflet tenting by dedicated softwares.

MA and TA areas, as well as tenting volumes, were higher in athletes compared with controls. MA area was significantly higher in athletes with MR compared with those without (8.2 ± 1.0 vs. 7.2 ± 1.0 cm2/m2, P < 0.05). Interestingly, athletes with MR also presented with a significantly higher TA area (7.2 ± 1.1 vs. 6.5 ± 1.1 cm2/m2, P < 0.05). Nonplanar angle describing the MA’s saddle shape was less obtuse in athletes without MR, whereas the values of athletes with MR were comparable with controls. The exercise-induced relative increases in left ventricular (35 ± 25%) and left atrial (40 ± 29%) volumes were similar; however, the increment in the MA area was disproportionately higher (63 ± 23%, overall P < 0.001). The relative increase in TA area (40 ± 23%) was also higher compared with the increment in right ventricular volume (34 ± 25%, P < 0.05).

Atrioventricular annuli undergo a disproportionate remodeling in response to regular exercise. Athletic adaptation is characterized by both annular enlargement and increased leaflet tenting of both valves. There are differences in MA geometry in athletes presented with versus without FMR.

Financed by the Development of scientific workshops of medical, health sciences and pharmaceutical educations project (EFOP-3.6.3-VEKOP-16-2017-000099), Semmelweis University.

University and Doctoral School

Semmelweis University, Doctoral School of Theoretical and Translational Medicine

Supervisor

Dr. Kovács Attila

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

szóbeli

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

5932

Start

09:45

End

10:00

Authors (legacy)

Alexandra Fábián1,
1 Semmelweis University, Doctoral School of Theoretical and Translational Medicine