PhD Scientific Days 2021

CL_I_P: Clinical Medicine I. Posters

The Role Of Left Atrial Wall Thickness And Pulmonary Vein Anatomy In Success Of Pulmonary Vein Isolation Using The Close Protocol.

Előadó neve

Dr. Boussoussou, Melinda

Előadó munkahelye

Semmelweis University Heart and Vascular Center, Cardiovascular Imaging Research Group

Előadó telefonszáma

06206632859

Előadó e-mail címe

melinda.b.md@gmail.com

Az előadás címe

The Role Of Left Atrial Wall Thickness And Pulmonary Vein Anatomy In Success Of Pulmonary Vein Isolation Using The Close Protocol.

Szerző(k) neve és munkahelye

Melinda Boussoussou MD 1, Borbála Vattay MD 1, Bálint Szilveszter MD 1, Márton Kolossváry MD1, Milán Vecsey-Nagy MD 1, Zoltán Salló MD 1, Judit Simon MD 2, Gábor Orbán MD 1, Perge Péter MD 1, Piros Katalin MD 1, Nagy Klaudia Vivien MD 1, Osztheimer István MD 1, Pál Maurovich-Horvat MD 2, Béla Merkely MD 1, László Gellér MD 1, Nándor Szegedi MD 1

1: Semmelweis University Heart and Vascular Center, 1122 Budapest, Városmajor utca 68., Hungary
2: Medical Imaging Centre, 1082 Budapest, Korányi Sándor u. 2., Hungary

Bemutatás módja

Poszter

Szekció

Clinical Medicine I. Posters

Language of the presentation

Hungarian

Preferred session

Clinical Medicine

Összefoglaló szövege

Introduction: The CLOSE protocol is a novel contact-force guided technique for enclosing pulmonary veins in patients with atrial fibrillation (AF).
Aims: We sought to determine whether left atrial (LA) wall thickness (LAWT) and pulmonary vein (PV) dimensions, as assessed by coronary CT angiography (CTA), could influence the success-rate of first-pass isolation using the CLOSE protocol.
Methods: In a single-center, prospective study, we enrolled 94 consecutive patients with symptomatic, drug-refractory AF who underwent initial radiofrequency catheter ablation. Pre-procedural CTA was performed in all cases. Additionally, the diameter and area of the PV orifices were obtained.
Results: A total of 94 patients were included in the analysis with a mean CHA2DS2-VASc score of 2.1±1.5 (mean age 62.4±12.6 years, 39.5% female, 38.3% persistent AF). Mean procedure time was 81.2±19.3 minutes. Complete isolation of all four PVs was achieved in 100% of patients. First-pass isolation rate was 76% and 71% for the right-sided PVs and the left-sided PVs, respectively. No difference was found regarding comorbidities and imaging parameters between those with and without first-pass isolation. LAWT (mean of 11 regions or separately) had no effect on the acute procedural outcome on logistic regression analysis (all p≥0.05). Out of all assessed parameters, only RSPV diameter was associated with a higher rate of successful right-sided first pass isolation (OR:1.00, p=0.04).
Conclusion: The CLOSE protocol in AF patients resulted in a high acute procedural success rate in terms of first-pass isolation, independently from the thickness of the LA wall. RSPV diameter could influence the probability of first-pass isolation.
Funding: EFOP-3.6.3-VEKOP-16-2017-00009, “NTP-NFTÖ” (Nemzeti Tehetség Program, Nemzet Fiatal Tehetségeiért Ösztöndíj) program of the Ministry of Human Capacities in Hungary (EMMI).

University and Doctoral School

Semmelweis University, Doctoral School of Theoretical and Translational Medicine

Supervisor

Dr. Maurovich Horvat Pál

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

4775

Start

10:48

End

10:51

Authors (legacy)

Melinda Boussoussou MD 1, Borbála Vattay MD 1, Bálint Szilveszter MD 1, Márton Kolossváry MD1, Milán Vecsey-Nagy MD 1, Zoltán Salló MD 1, Judit Simon MD 2, Gábor Orbán MD 1, Perge Péter MD 1, Piros Katalin MD 1, Nagy Klaudia Vivien MD 1, Osztheimer István MD 1, Pál Maurovich-Horvat MD 2, Béla Merkely MD 1, László Gellér MD 1, Nándor Szegedi MD 1

1: Semmelweis University Heart and Vascular Center, 1122 Budapest, Városmajor utca 68., Hungary
2: Medical Imaging Centre, 1082 Budapest, Korányi Sándor u. 2., Hungary