PhD Scientific Days 2021

Budapest, 7-8 July 2021

CL_II_P: Clinical Medicine II. Posters

Prospective analysis of FORECAST pilot score for estimation the early mortality in resuscitated patients

Előadó neve

Dr. Kiss, Boldizsar

Előadó munkahelye

Semmelweis University, Heart and Vascular Centre

Előadó telefonszáma

+36302867060

Előadó e-mail címe

kiss.boldizsar@med.semmelweis-univ.hu

Az előadás címe

Prospective analysis of FORECAST pilot score for estimation the early mortality in resuscitated patients

Szerző(k) neve és munkahelye

Boldizsár Kiss 1 , Bettina Nagy 1 , Gábor Tamás Dér 1, Béla Merkely 1, Endre Zima 1

1 Semmelweis University, Heart and Vascular Centre, Budapest

Bemutatás módja

Poszter

Szekció

Clinical Medicine II. Posters

Language of the presentation

Hungarian

Preferred session

Clinical Medicine

Összefoglaló szövege

Introduction: Sudden cardiac death (SCD) is one of the most significant cardiovascular causes of death. In the treatment of SCD – following a successful cardiopulmonary resuscitation (CPR) – patients often require complex intensive care. Currently there are only a few validated score systems given to quickly and reliably estimate the mortality risk and the optimal short and long term outcome of these patients.

Aims: Our aim was to develop a scoring system that quickly, accurately, and reliably estimates mortality in patients undergoing CPR and intensive care in the first few hours. In addition to cardiovascular risk factors that indicate haemodynamic instability, we also investigated factors, that potentially worsen the outcome of CPR.

Method: Between 2019 and 2020, we enrolled 49 patients in our prospective, non-interventional clinical trial who underwent successful CPR, were 18 years of age, and were treated in the cardiology ICU of the Heart and Vascular Centre. During the care of these patients, data on anamnestic, CPR conditions, and intensive care were analyzed according to scheduled sampling. The FORECAST maximum point is 16.

Results: According to Cox-regression early mortality was significantly reduced by age under 75 years (p:0.065, OR:0,448 [0,191-1,051]), eGFR above 60 (p:0.025, OR:0,429 [0,204-0,901]), and initial shockable rhythm (p:0.066, OR:0.501 [0.240-1.046]). Early mortality was significantly increased by age over 75 years (p:0.065, OR: 2.235 [0.952-5.246]), previous CABG surgery (p:0.022, OR: 3.302[1.138-9.585]), eGFR below 60 (p:0.025, OR:2.332 [1.110-4.902]), and non-shockable initial rhythm (p:0.066, OR:1.997[0.965-4.168]).

Conclusion: The early mortality of a successfully resuscitated patient is clearly determined by age, previous CABG surgery, eGFR at admission, and initial rhythm. For the other variables, with this number of items, we did not find a clear correlation with early mortality. Further refinement of the score system is still needed with the continuation of the prospective study.

University and Doctoral School

Semmelweis University, Doctoral School of Theoretical and Translational Medicine

Supervisor

Prof. Zima Endre István

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

6033

Start

12:59

End

13:02

Authors (legacy)

Boldizsár Kiss 1 , Bettina Nagy 1 , Gábor Tamás Dér 1, Béla Merkely 1, Endre Zima 1

1 Semmelweis University, Heart and Vascular Centre, Budapest