PhD Scientific Days 2022

Clinical Medicine II.

Ablation-index guided high-power radiofrequency versus second-generation cryoballoon ablation for pulmonary vein isolation – a large volume, single-center experience

Előadó neve

Dr. Kássa, Krisztián

Előadó munkahelye

Gottsegen National Cardiovascular Center

Előadó telefonszáma

+36301087165

Előadó e-mail címe

krisztian.kassa@gokvi.hu

Az előadás címe

Ablation-index guided high-power radiofrequency versus second-generation cryoballoon ablation for pulmonary vein isolation – a large volume, single-center experience

Szerző(k) neve és munkahelye

Krisztian Kassa1,2, Zsofia Nagy2, Zoltan Som2, Csaba Foldesi2, Attila Kardos2
1 Semmelweis University, Budapest, Hungary
2 Gottsegen National Cardiovascular Center, Budapest, Hungary

Bemutatás módja

Szóbeli

Szekció

Clinical Medicine II.

Language of the presentation

English

Preferred session

Clinical Medicine

Összefoglaló szövege

Introduction: To date, point-by-point radiofrequency and cryoballoon ablation are the most commonly used techniques for pulmonary vein isolation (PVI).
Aims: This study aimed to compare the efficacy and safety of ablation-index (AI) guided high-power radiofrequency (HRF) and second-generation cryoballoon (CB2) ablation in patients with atrial fibrillation (AF).
Method: Symptomatic patients (61% male, mean age: 62±10 years, CHA2DS2-VASc score: 2.1±1.5) with paroxysmal (62%) or persistent (38%) AF underwent PVI by HRF (n=103) or CB2 (n=273). In the HRF group, 50W power was used, aiming AI values 550 at the anterior and 400 at the posterior wall (power-controlled mode, target inter-lesion distance <6 mm). For cryoablation, a strategy of 180/240 second freeze time was used on the right/left sided pulmonary veins.
Results: The recurrence rate did not differ significantly between the groups after 12 months (HRF: 22% vs. CB2: 28%, p=0.089). Major complication rate was below 1% using each ablation strategy. Procedural time was significantly shorter in the CB2 group (92±30 min vs. 51.3±14.7 min, p<0.001), while both fluoroscopy time (5.7±4.6 min vs. 10.0±4.9 min, p<0.001) and fluoroscopy dose (401±514 cGycm2 vs. 1857±1898 cGycm2, p<0.001) were significantly higher using cryoballoon ablation.
Conclusion: AI guided HRF and CB2 ablation are comparable regarding clinical efficacy and safety. HRF PVI procedures take longer time, however radiation exposure is markedly reduced compared to CB2 ablation.
Funding: The authors received no financial support for the research, authorship, and/or publication of this study.

University and Doctoral School

Semmelweis University, Károly Rácz Doctoral School of Clinical Medicine

Supervisor

Dr Attila Kardos PhD

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

szóbeli

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

6788

Start

14:30

End

14:45

Authors (legacy)

Krisztian Kassa1,2, Zsofia Nagy2, Zoltan Som2, Csaba Foldesi2, Attila Kardos2
1 Semmelweis University, Budapest, Hungary
2 Gottsegen National Cardiovascular Center, Budapest, Hungary