PhD Scientific Days 2022

Clinical Medicine VII. (Poster discussion will take place in the Aula during the Coffee Break)

The impact of SARS-CoV-2 infection on the outcome of acute ischemic stroke - a retrospective cohort study

Előadó neve

Dr. Takács, Tímea Tünde

Előadó munkahelye

Semmelweis University, Department of Neurology

Előadó telefonszáma

06206701432

Előadó e-mail címe

takacsttm@gmail.com

Az előadás címe

The impact of SARS-CoV-2 infection on the outcome of acute ischemic stroke - a retrospective cohort study

Szerző(k) neve és munkahelye

Tímea Tünde Takács1,3*, Ádám József Berki1, Péter Pál Böjti1,2,3, Rita Stang1,3, Pablo Antonio Fritz-Reunes1, Luiz Schnekenberg4, Timo Siepmann4,5, Alexandra Pintér5,6, Szabolcs Szatmári1, Dániel Bereczki1,7,8 and Bence Barna Gunda1,3
1 Semmelweis University, Department of Neurology, Budapest, Hungary
2 National Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary
3 Semmelweis University, “János Szentágothai” Doctoral School of Neurosciences, Budapest, Hungary
4 University Hospital Carl Gustav Carus, Department of Neurology, Dresden, Germany
5 Division of Health Care Sciences, Center for Clinical Research and Management Education, Dresden Inter-na-tional University, Dresden, Germany
6 Semmelweis University, Department of Family Medicine, Budapest, Hungary
7 European Academy of Neurology, EANcore COVID-19 Task Force, Vienna, Austria
8 MTA-SE Neuroepidemiological Research Group, Budapest, Hungary

Bemutatás módja

Poszter

Szekció

Clinical Medicine VII. (Poster discussion will take place in the Aula during the Coffee Break)

Language of the presentation

English

Preferred session

Clinical Medicine

Összefoglaló szövege

Introduction: Acute ischemic stroke (AIS) is a frequent complication of coronavirus disease (COVID-19), but the prognosis of these patients is poorly understood. Aims: To explore the impact of COVID-19 on neurological outcomes in AIS patients. Methods: A comparative retrospective cohort study was conducted on 32 consecutive AIS patients with and 51 without COVID-19 between the 1st of March 2020 and the 1st of May 2021. The evaluation was based on a detailed chart review for demographic data, medical history, stroke severity, cranial and vessel imaging results, laboratory parameters, COVID-19 severity, hospitalization time, in-hospital mortality, and functional deficits at discharge (modified Rankin Scale, mRS). Results: COVID-19 AIS patients showed tendency to worse initial neurological deficit (NIHSS 9 (3-13) vs. 4 (2-10); p=0.06), higher rate of large vessel occlusion (LVO; 13/32 vs. 14/51; p=0.21), had prolonged hospitalization (19.4 ± 17.7 vs. 9.7 ± 7 days; p=0.003), had lower chance of functional independence (mRS≤2) (12/32 vs. 32/51; p=0.02) and showed higher in-hospital mortality (10/32 vs. 6/51; p=0.02). In COVID-19 AIS patients, LVO was more common with COVID-19 pneumonia than without (55.6% vs. 23.1%; p=0.139). Conclusion: COVID-19-related AIS carries a worse prognosis. COVID-19 with pneumonia seems to be associated with a higher rate of LVO.
Funding: This research received no external funding.

University and Doctoral School

Semmelweis University, János Szentágothai Doctoral School of Neurosciences

Supervisor

Dr Bence Gunda

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

6799

Start

14:00

End

14:05

Authors (legacy)

Tímea Tünde Takács1,3*, Ádám József Berki1, Péter Pál Böjti1,2,3, Rita Stang1,3, Pablo Antonio Fritz-Reunes1, Luiz Schnekenberg4, Timo Siepmann4,5, Alexandra Pintér5,6, Szabolcs Szatmári1, Dániel Bereczki1,7,8 and Bence Barna Gunda1,3
1 Semmelweis University, Department of Neurology, Budapest, Hungary
2 National Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary
3 Semmelweis University, “János Szentágothai” Doctoral School of Neurosciences, Budapest, Hungary
4 University Hospital Carl Gustav Carus, Department of Neurology, Dresden, Germany
5 Division of Health Care Sciences, Center for Clinical Research and Management Education, Dresden Inter-na-tional University, Dresden, Germany
6 Semmelweis University, Department of Family Medicine, Budapest, Hungary
7 European Academy of Neurology, EANcore COVID-19 Task Force, Vienna, Austria
8 MTA-SE Neuroepidemiological Research Group, Budapest, Hungary