PhD Scientific Days 2022

Clinical Medicine VI. (Poster discussion will take place on the terrace of the room during the Coffee Break)

The Effect Of Quantum Iterative Reconstruction Levels On Coronary Calcium Scores Using Dual-source Photon-counting Detector Computed Tomography: In Vivo Experience

Előadó neve

Dr. Boussoussou, Melinda

Előadó munkahelye

Semmelweis University Heat and Vascular Center

Előadó telefonszáma

06206632859

Előadó e-mail címe

melinda.b.md@gmail.com

Az előadás címe

The Effect Of Quantum Iterative Reconstruction Levels On Coronary Calcium Scores Using Dual-source Photon-counting Detector Computed Tomography: In Vivo Experience

Szerző(k) neve és munkahelye

Melinda Boussoussou, MD 1, Borbála Vattay, MD 1, Andrea Bartykowszki, MD PhD 2, Márton Kolossváry, MD PhD 3, Gábor Konkoly 2, Milán Vecsey-Nagy, MD 2, Anikó Kubovje MSc 4, Béla Merkely MD, PhD, MSc, DSc, FESC, FACC 2, Pal Maurovich-Horvat MD, PhD, MPH, FSCCT 4, Bálint Szilveszter MD PhD 1

1: MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Centre, Semmelweis University, Budapest, Hungary,
2: Heart and Vascular Centre, Semmelweis University, Budapest, Hungary
3: Cardiovascular Imaging Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA,
4: Medical Imaging Centre, Semmelweis University, Budapest, Hungary.

Bemutatás módja

Poszter

Szekció

Clinical Medicine VI. (Poster discussion will take place on the terrace of the room during the Coffee Break)

Language of the presentation

Hungarian

Preferred session

Clinical Medicine

Összefoglaló szövege

Introduction: Coronary calcium score is a well-established risk factor of adverse cardiac events. Novel dual-source photon-counting detector CT (PCD-CT) technology has been introduced in clinical practice recently, however data are limited regarding the impact of quantum iterative reconstruction (QIR) algorithm on coronary calcium score (CACS).
Aims: To assess the difference in CACS using images without QIR and QIR levels of 1 to 4.
Methods: Native coronary CT images were acquired using a dual-source PCD-CT in 24 patients referred for coronary CT angiography due to stable chest pain (16 male (66.6%), mean age 59.5 ± 12.9). Images were obtained using a high-pitch helical protocol (turbo flash) using a tube voltage of 120 kV in the multi-energy (QuantumPlus) mode. CACS was quantified by a single reader using a semi-automated software tool (Syngo.via VB60A_SP1, Siemens Healthineers; Forchheim, Germany). Images were reconstructed without QIR or QIR level of 1 (lowest) to 4 (highest) on 70 keV, using Qr36 kernel with 3 mm slice thickness and 1.5 mm increment. After an initial correction for beam-hardening and geometric cone-beam artefacts, QIR additionally reduces image noise at different strength levels. The difference between reconstructions were compared using the Friedman test and post hoc pairwise Wilcoxon signed rank test with Bonferroni correction.
Results: Coronary calcium scores decrease substantially with increasing QIR levels as compared to QIR zero reconstructions: 199.5 ± 380.5 for QIR=0 vs 185.8 ± 357.8 for QIR=1 vs 181.3 ± 351.4 for QIR=2 vs 177.3 ± 345.2 for QIR=3 vs 173.5 ± 339.7 for QIR=4 (p<0.01 for each comparison). Mean difference increased accordingly by increasing QIR levels as compared images without QIR: 13.7 for QIR=1, 18.3 for QIR=2, 22.2 for QIR=3 and 26.0 for QIR=4.
Conclusions: Different QIR reconstructions influenced CACS significantly. Further studies are warranted to define the impact of QIR on CACS based risk
reclassification.

University and Doctoral School

Semmelweis University, Doctoral School of Theoretical and Translational Medicine

Supervisor

Dr. Maurovich-Horvat Pál

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

4775

Start

11:05

End

11:10

Authors (legacy)

Melinda Boussoussou, MD 1, Borbála Vattay, MD 1, Andrea Bartykowszki, MD PhD 2, Márton Kolossváry, MD PhD 3, Gábor Konkoly 2, Milán Vecsey-Nagy, MD 2, Anikó Kubovje MSc 4, Béla Merkely MD, PhD, MSc, DSc, FESC, FACC 2, Pal Maurovich-Horvat MD, PhD, MPH, FSCCT 4, Bálint Szilveszter MD PhD 1

1: MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Centre, Semmelweis University, Budapest, Hungary,
2: Heart and Vascular Centre, Semmelweis University, Budapest, Hungary
3: Cardiovascular Imaging Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA,
4: Medical Imaging Centre, Semmelweis University, Budapest, Hungary.