PhD Scientific Days 2022

Clinical Medicine IV.

Immediate-Type Reactions in Patch Test

Előadó neve

Dr. Németh, Dominik

Előadó munkahelye

Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest

Előadó telefonszáma

06204716311

Előadó e-mail címe

dominik.nth@gmail.com

Az előadás címe

Immediate-Type Reactions in Patch Test

Szerző(k) neve és munkahelye

1. dr. Dominik Németh, Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest; Károly Rácz Doctoral School of Clinical Medicine, Semmelweis University, Budapest

2. dr. Anikó Kovács, Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest

3. dr. Dóra Solymosi, Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest; Károly Rácz Doctoral School of Clinical Medicine, Semmelweis University, Budapest

4. Prof. emer. Erzsébet Temesvári, Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest

5. dr. Györgyi Pónyai PhD, Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest

Bemutatás módja

Szóbeli

Szekció

Clinical Medicine IV.

Language of the presentation

English

Preferred session

Clinical Medicine

Összefoglaló szövege

Introduction: Patch test is the standard diagnostic tool for verifing contact hypersensitivity in the daily dermatological allergology practice. Not only delayed-type, but immediate-type contact reactions can be observed as well. Patch test is commonly indicated in several dermatoses, thus confirming the underlying contact allergy in the backgound of the skin diseases.

Aims: Our study aimed to analyse the clinical characteristics of our patch tested patient population with at least one verified immediate-type contact reaction.

Method: Patients were patch tested in the Allergy Outpatient Unit of Department of Dermatology, Venereology and Dermatooncology of Semmelweis University between 2007-2020. The European Environmental Baseline Series (EEBS) and the Complementary Fragrance Series (CFS) allergens were used. The tests were made in accordance with international methodological standards for patch tests in 48-hour occlusion. Evaluation of the skin reactions happened in 20-60 minutes, 48, 72, 96 hours and on the 7th day.

Results: During the 14-year period 5543 patients were patch tested with the EEBS and 3124 with the CFS at the same time. Among them 384 patients had at least one immediate-type positivity. Female predominace was observed (81.8%). Most patients belonged to the age group of 41-50 (24.0%). 50.8% of the patients had one, 35.7% had two, and 13.5% had three or more immediate-type contact reactions. The most common contact allergens were benzoic acid (86.2%), sorbic acid (38.8%), and balsam of Peru (30.2%). Regarding delayed-type co-hypersensitivities nickel, fragrances, and preservatives can be mentioned.

Conclusion: In case of typical anamnestic features, when immediate-type contact reactions are suspected, patch tests are advised to perform. Patients can be educated about the different sources of allergen exposures after identifing the provoking ones, which should be avoided lifelong in order to prevent future allergic symptoms.

Funding: Semmelweis 250+ PhD Excellency Scholarship (EFOP-3.6.3-VEKOP-16-2017-00009)

University and Doctoral School

Semmelweis University, Károly Rácz Doctoral School of Clinical Medicine

Supervisor

dr. Györgyi Pónyai PhD, associate professor

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

szóbeli

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

5118

Start

15:00

End

15:15

Authors (legacy)

1. dr. Dominik Németh, Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest; Károly Rácz Doctoral School of Clinical Medicine, Semmelweis University, Budapest

2. dr. Anikó Kovács, Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest

3. dr. Dóra Solymosi, Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest; Károly Rácz Doctoral School of Clinical Medicine, Semmelweis University, Budapest

4. Prof. emer. Erzsébet Temesvári, Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest

5. dr. Györgyi Pónyai PhD, Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest