PhD Scientific Days 2022

Clinical Medicine VI. (Poster discussion will take place on the terrace of the room during the Coffee Break)

Results of the Semmelweis Post-COVID athletes' registry: the predictors of long COVID

Előadó neve

Dr. Vencel, Juhász

Előadó munkahelye

Heart and Vascular Center of Semmelweis University

Előadó telefonszáma

+36206701718

Előadó e-mail címe

vencel.juhasz@gmail.com

Az előadás címe

Results of the Semmelweis Post-COVID athletes' registry: the predictors of long COVID

Szerző(k) neve és munkahelye

Vencel Juhász MD(a), Liliána Szabó MD(a), Attila Pavlik MD, PhD (b), András Tállay MD, PhD (b), Dorottya Balla(a) ,Orsolya Kiss MD, PhD (a,b), Máté Babity MD(a), Nóra Sydó MD, PhD (a,b), Emese Csulak MD (a), András Benczúr PhD (c),Anna Országh(c), Zsófia Gregor MD(a), Dávid Becker MD, PhD (a), Béla Merkely MD, PhD, Prof (a,b), Hajnalka Vágó MD, PhD (a,b)

a) Semmelweis University – Heart and Vascular Center – Budapest, Hungary
68 Varosmajor St, Budapest, H-1122, Hungary
b) Semmelweis University – Department of Sports Medicine – Budapest, Hungary
9-11 Gaal-Jozsef Rd, Budapest, H-1122, Hungary
c) Institute for Computer Science and Control – Budapest, Hungary
13 Kende St, Budapest, H-1111, Hungary

Bemutatás módja

Szóbeli

Szekció

Clinical Medicine VI. (Poster discussion will take place on the terrace of the room during the Coffee Break)

Language of the presentation

English

Preferred session

Clinical Medicine

Összefoglaló szövege

Introduction: At the pandemic's beginning, significant concern has risen about the prevalence of myocardial involvement after SARS-CoV-2 infection. Long COVID syndrome may also substantially affect athletic performance.
Aims: Our goal was to assess the cardiovascular burden of SARS-CoV-2 in a large cohort of athletes and to identify factors that might affect the disease course.
Methods: We included 633 athletes in our study on whom we performed extensive cardiology examinations after recovering from SARS-CoV-2 infection. More than half of the athletes (n=322) returned for a follow-up examination median of 107 days after the commencement of their infection.
Results: Troponin T positivity was as low as 1.4% of the athletes, where the subsequently performed examinations did not show definitive, ongoing myocardial injury. Altogether, 31% of the athletes' rapid training rebuild was hindered by persistent or reoccurring symptoms. Female athletes reported a higher prevalence of return to play (RTP) symptoms than their male counterparts (34% vs 19%, p=0.005). The development of long COVID symptoms was independently predicted by age and acute symptoms (palpitation, chest pain, cough) in a multiple regression model (AUC 0.81, CI 0.759-0.847). Athletes presenting with either or both cough and ferritin levels higher than >150 ug/L had a 4.1x (CI 1.78-9.6, p=0.001) higher odds ratio to develop persistent symptoms.
Conclusion: While SARS-CoV-2 rarely affects the myocardium in athletes, about one in three athletes experience symptoms beyond the acute phase. Identifying those athletes with a predisposition to developing long-standing symptoms may aid clinicians and trainers to find the optimal return to play timing and training load rebuild pace.
Funding:
-Project no. NVKP_16-1–2016-0017 ('National Heart Program') - National Research, Development, and Innovation Fund of Hungary, NVKP_16 funding scheme.
- Thematic Excellence Programme (2020-4.1.1.-TKP2020) - Ministry for Innovation and Technology in Hungary, within the framework of the Therapeutic Development and Bioimaging thematic programs - Semmelweis University, Artificial Intelligence National Laboratory Programme.".
- National Research, Development, and Innovation Office (NKFIH) of Hungary (K135076 to BM)
- National Research, Development, and Innovation Office (NKFIH) of Hungary (2020-1.1.6-JÖVŐ-2021-00013).

University and Doctoral School

Semmelweis University, Doctoral School of Theoretical and Translational Medicine

Supervisor

Dr. Hajnalka Vágó PhD

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

szóbeli

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

6002

Start

09:30

End

09:45

Authors (legacy)

Vencel Juhász MD(a), Liliána Szabó MD(a), Attila Pavlik MD, PhD (b), András Tállay MD, PhD (b), Dorottya Balla(a) ,Orsolya Kiss MD, PhD (a,b), Máté Babity MD(a), Nóra Sydó MD, PhD (a,b), Emese Csulak MD (a), András Benczúr PhD (c),Anna Országh(c), Zsófia Gregor MD(a), Dávid Becker MD, PhD (a), Béla Merkely MD, PhD, Prof (a,b), Hajnalka Vágó MD, PhD (a,b)

a) Semmelweis University – Heart and Vascular Center – Budapest, Hungary
68 Varosmajor St, Budapest, H-1122, Hungary
b) Semmelweis University – Department of Sports Medicine – Budapest, Hungary
9-11 Gaal-Jozsef Rd, Budapest, H-1122, Hungary
c) Institute for Computer Science and Control – Budapest, Hungary
13 Kende St, Budapest, H-1111, Hungary