PhD Scientific Days 2022

Mental Health Sciences II. (Poster discussion will take place in the Aula during the Coffee Break)

Meta-analysis Suggests that Affective Temperaments May Predict Treatment Adherence Both in Psychiatric and Non-psychiatric Patients

Előadó neve

Szabó, Georgina

Előadó munkahelye

SE Mentális Egészségtudományok Doktori Iskola

Előadó telefonszáma

+36 203622216

Előadó e-mail címe

szabo.georgina@phd.semmelweis.hu

Az előadás címe

Meta-analysis Suggests that Affective Temperaments May Predict Treatment Adherence Both in Psychiatric and Non-psychiatric Patients

Szerző(k) neve és munkahelye

Georgina Szabó1, Michele Fornaro2, Péter Döme3,4, Szabolcs Várbíró5, Xénia Gonda3,6

1 Doctoral School of Mental Health Sciences, Semmelweis University, Budapest, Hungary
2 New York Psychiatric Institute, Columbia University, New York City, NY 10032, USA
3 Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
4 National Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary
5 Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
6 NAP-2-SE New Antidepressant Target Research Group, Hungarian Brain Research Program, Semmelweis University, Budapest, Hungary

Bemutatás módja

Poszter

Szekció

Mental Health Sciences II. (Poster discussion will take place in the Aula during the Coffee Break)

Language of the presentation

Hungarian

Preferred session

Mental Sciences

Összefoglaló szövege

Background: Among risk factors for treatment non-adherence, there is growing interest in associations with affective temperament types, particularly based on assessment with the Temperament evaluation of Memphis, Pisa, Paris and San Diego (TEMPS-A) questionnaire.
Aim: As research on this topic has not been reviewed systematically, we synthesized relevant, reported research findings and performed meta-analysis.
Methods: Systematic searching on Scopus, WoS, OVID MedLine and PubMed using the search term "TEMPS-A" AND (adherence OR compliance) identified peer-reviewed reports pertaining to associations of treatment adherence with affective temperament types evaluated with TEMPS-A self rating scale. We summarized available findings and applied quantitative meta-analytic methods to compare scale scores in non-adherent versus adherent subjects. Reports that provided quantitative data both for the specific affective temperament types (TEMPS-A subscales) and for treatment adherence or compliance measures (MMAS, MARS or other), and also the association between them were included in the analysis. No restrictions on study design, participants age or treatment type were made. Findings of associations of TEMPS-A scores and treatment adherence were evaluated to test the hypothesis that significantly different TEMPS-A subcale ratings would be found among subjects with high adherence from among low adherence subjects under matched circumstances. Data was analyzed by random-effects, meta-analytic pooling based on standardized mean differences (SMDs) in scores between adherent and non-adherent subjects. Meta-analytic findings are reported as pooled-SMDs with confidence intervals. All statistical analyses were implemented using R package metaphor v.3.0.
Results: Based on 9 studies meeting inclusion criteria (total n=1138 subjects), cyclothymic, depressive, and irritable temperament scores were significantly higher with medication non-adherence in both psychiatric and non-psychiatric patient samples compared to adherent samples. Limitations: Relatively low number of eligible studies and high level of methodological heterogeneity in adherence measurement.
Conclusions: Cyclothymic, depressive, and irritable temperament scores might have a potential predictive value on treatment adherence and therefore on overall treatment outcome as a consequence.

University and Doctoral School

Semmelweis University, Doctoral School of Mental Health Sciences

Supervisor

Dr. Gonda Xénia, Dr. Várbíró Szabolcs

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

6928

Start

13:10

End

13:15

Authors (legacy)

Georgina Szabó1, Michele Fornaro2, Péter Döme3,4, Szabolcs Várbíró5, Xénia Gonda3,6

1 Doctoral School of Mental Health Sciences, Semmelweis University, Budapest, Hungary
2 New York Psychiatric Institute, Columbia University, New York City, NY 10032, USA
3 Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
4 National Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary
5 Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
6 NAP-2-SE New Antidepressant Target Research Group, Hungarian Brain Research Program, Semmelweis University, Budapest, Hungary