PhD Scientific Days 2022

Clinical Medicine II.

Complications in the PFO-closure program of the Neurocardiology group at the Heart and Vascular Centre of Semmelweis University

Előadó neve

Dr. Henriette, Mészáros

Előadó munkahelye

Heart and Vascular Centre of Semmelweis University

Előadó telefonszáma

+36302957812

Előadó e-mail címe

meszaros.henriette0923@gmail.com

Az előadás címe

Complications in the PFO-closure program of the Neurocardiology group at the Heart and Vascular Centre of Semmelweis University

Szerző(k) neve és munkahelye

Henriette Mészáros1, Ábrahám Pál2, Andrea Ágnes Molnár2, Dorottya Pásztor2, Sándor Nardai1, Béla Merkely1
1 Heart and Vascular Centre , Cardiology, Semmelweis University, Budapest
2 Heart and Vascular Centre , Cardiology, Semmelweis University, Budapest

Bemutatás módja

Szóbeli

Szekció

Clinical Medicine II.

Language of the presentation

English

Preferred session

Clinical Medicine

Összefoglaló szövege

Introduction: PFO-closure is an effective intervention for secondary prevention of related ischaemic strokes. Our centre has been performing closures since 2018 with high success (94%) and low complication (3.0%) rates.
Aims: We aimed to asses and analyse the complications of the closures until January 2022.
Methods: We performed a retrospective clinical data analysis. Longer than 30 seconds of atrial fibrillation (AF) episodes were considered clinically relevant. The other complications were discovered using imaging techniques.
Results: We had 155 successful closures (94 %). Among the 5 complications, there were 3 AF-s, 1 device dislocation and 1 device thrombus. Only the intraoperative AF required electrical cardioversion. After it we monitored the patient with 30-day-Holter device, which did not detect any AF. We found two AF cases in the first postoperative month. In the first case, there was no recurrent arrhythmia, but the paroxysms of our other patient recurred despite antiarrhythmic drug treatment, therefore we plan ablation. All of these AF patients were administered oral anticoagulants (OAC). The device dislocation occurred in the
case of an atrial septal aneurysm, and the dislodged device did not cause any obstruction. It was removed percutaneously from the abdominal aorta, and we implanted a new device during the same session. Intraoperative transoesophageal echocardiography (TEE) identified in another case a non-symptomatic thrombus on the device, so we intensified the intraoperative heparin treatment, and indicated OAC for one month. Control TEE described normal device status.
Conclusion: Similarly to the multicentre studies, we also confirm, that the PFO-closure is safe with low complication rate. We could conclude, that it is important to select the most appropriate device. The long-term clinical relevance of triggered AF is doubted, so the treatment is not clearly defined yet. We have to find imaging markers in the future to predict its occurrence.
Funding: Non declared.

University and Doctoral School

Semmelweis University, Doctoral School of Theoretical and Translational Medicine

Other university and doctoral school, not listed above

Semmelweis Translational Medicine Program

Supervisor

Professor Béla Merkely, Sándor Nardai

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

szóbeli

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

6930

Start

16:00

End

16:15

Authors (legacy)

Henriette Mészáros1, Ábrahám Pál2, Andrea Ágnes Molnár2, Dorottya Pásztor2, Sándor Nardai1, Béla Merkely1
1 Heart and Vascular Centre , Cardiology, Semmelweis University, Budapest
2 Heart and Vascular Centre , Cardiology, Semmelweis University, Budapest