PhD Scientific Days 2022
Budapest, 6-7 July 2022
Clinical Medicine V. (Poster discussion will take place in the Aula during the Coffee Break)
The Presence of Adverse Atherosclerotic Coronary Plaque Features is Associated with Diabetes
Előadó neve
Dr. Simon, Simon
Előadó munkahelye
Semmelweis University
Előadó telefonszáma
(20) 825 8056
Előadó e-mail címe
juditsimon21@gmail.com
Az előadás címe
The Presence of Adverse Atherosclerotic Coronary Plaque Features is Associated with Diabetes
Szerző(k) neve és munkahelye
Judit Simon1,2, Márton Kolossváry2, Bálint Szilveszter2, Anna
Sára Kardos1, Emese Zsarnóczay1, Melinda Boussoussou2, Borbála Vattay2, Béla Merkely,2 Pál Maurovich-
Horvat1,2
1 Medical Imaging Centre, Semmelweis University, Budapest, Hungary
2 Heart and Vascular Center, Semmelweis University, Budapest, Hungary
Bemutatás módja
Poszter
Szekció
Clinical Medicine V. (Poster discussion will take place in the Aula during the Coffee Break)
Language of the presentation
English
Preferred session
Clinical Medicine
Összefoglaló szövege
Introduction: Diabetes mellitus (DM) is associated with increased cardiovascular morbidity and mortality. However, there is a lack of data about the prevalence of high-risk coronary artery plaques in patients with DM.
Aims: In our study we aimed to compare the prevalence of adverse atherosclerotic coronary artery plaque features between patients with and without DM.
Methods: We have analyzed the data of patients who underwent coronary computed tomography angiography (CCTA) between October 2012 and December 2020. Patients were divided into two groups based on the presence of DM.
Results: After exclusion, 11357 patients (47.6% men) were included in our study. Prevalence of DM was 14.5%. There were significant differences in age (63.2±9.5 vs 58.1±12.2 years, <0.001) and major cardiovascular risk factors between the two groups (all <0.05). While 29.6% of patients without DM had at least one high risk plaque, this rate was 38.9% in those with DM (positive remodeling: 19.6% vs 26.1%, low attenuation: 7.6% vs 10.2%, spotty calcium: 16.9% vs 21.6%, napkin-ring sign: 1.7% vs 2.6%, all p<0.05). Using multivariate analysis we found that DM increases the prevalence of any vulnerable plaque feature 1.26 (CI=1.13-1.41, p<0.001) times.
Conclusion: The prevalence of severe coronary artery stenosis and coronary plaques with adverse characteristics was higher in patients with DM. DM has been identified as an individual predictor of vulnerable plaque features.
University and Doctoral School
Semmelweis University, Doctoral School of Theoretical and Translational Medicine
Supervisor
Pál Maurovich-Horvat
Publication of my abstract
I give consent to the publication of my abstract on the website of the congress.
Kind
Szabad
Status
elfogadva
Accepted presentation method
poszter
Előadás fájl jóváhagyás
nem rendelkezett róla
Előadó
4770
Start
11:25
End
11:30
Authors (legacy)
Judit Simon1,2, Márton Kolossváry2, Bálint Szilveszter2, Anna
Sára Kardos1, Emese Zsarnóczay1, Melinda Boussoussou2, Borbála Vattay2, Béla Merkely,2 Pál Maurovich-
Horvat1,2
1 Medical Imaging Centre, Semmelweis University, Budapest, Hungary
2 Heart and Vascular Center, Semmelweis University, Budapest, Hungary