PhD Scientific Days 2022

Clinical Medicine VI. (Poster discussion will take place on the terrace of the room during the Coffee Break)

Cardiologist

Előadó neve

Dr. Tajti, Peter, PhD

Előadó munkahelye

Gottsegen Gyorgy National Cardiovascular Institute

Előadó telefonszáma

06303180892

Előadó e-mail címe

ptajti@gmail.com

Az előadás címe

Cardiologist

Szerző(k) neve és munkahelye

Peter Tajti, MD, PhD*†, Mohamed Ayoub, MD‡, Abdelkrim Ahres, MD†, Michael Behnes, MD§, Heinz Joachim Buettner, MD*, Prof. Franz-Josef Neumann, MD, PhD*, Kambis Mashayekhi, MD, PD*‖

* Department of Interventional Cardiology, Cardiology and Angiology II, University Heart Center Freiburg – Bad Krozingen, Germany
† Gottsegen György National Cardiovascular Institute – Budapest, Hungary
‡ University Heart and Diabetes Center North-Rhine and Westphalia, Department of Cardiology and Angiology – Bochum, Germany
§ First Department of Medicine, University Medical Center Mannheim – Mannheim, Germany

Bemutatás módja

Poszter

Szekció

Clinical Medicine VI. (Poster discussion will take place on the terrace of the room during the Coffee Break)

Language of the presentation

English

Preferred session

Clinical Medicine

Összefoglaló szövege

Background: The prognostic impact on in-hospital and long-term outcomes of contrast-associated acute kidney injury (CA-AKI) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited studies.
Methods: We examined 2707 consecutive procedures performed in a referral CTO center between 2015 and 2019. CA-AKI was defined as an increase in serum creatinine ≥0.3 mg/dl or ≥50% within 48 h post-PCI. Primary endpoints were major adverse cardiac and cerebrovascular events (MACCE) in-hospital (composite of all-cause death, myocardial infarction [MI], target vessel revascularization [TVR], stroke) and at 1-year of follow-up.
Results: The overall incidence of CA-AKI was 11.5%, respectively. Patients with CA-AKI (n=312) had more severe comorbidities in comparison with patients without CA-AKI (n=2,395). Technical (87.2% vs. 90.5%, p=0.056) success was similar in both groups, whereas procedural (84.3% vs. 89.7%, p=0.004) success was lower in the CI-AKI group. In-hospital MACCE was 1.3%, respectively, and were comparable in patients with and without CA-AKI (1.6% vs. 1.3%, p=0.655), however, pericardial tamponade requiring pericardiocentesis were significantly higher in patients with CA-AKI (2.2% vs. 0.5%, p=0.001). In multivariate analysis, CA-AKI was not independently associated with higher risk for in-hospital MACCE (adjusted odds ratio [OR] 1.34, confidence intervals [CI] 0.45-3.19, p=0.563). At median follow-up time of 14 months (interquartile range [IQR], 11 to 35 months), 1-year MACCE was significantly higher in patients with versus without CA-AKI (20.8% vs. 12.8%, p<0.001), and CA-AKI has significantly increased the risk for 1-year MACCE (adjusted hazard ratio [HR] 1.52, CI 1.05-2.15, p=0.029) following CTO PCI.
Conclusions: Contrast-associated acute kidney injury commonly occurs in patients undergoing CTO PCI that may lead to an increased risk for 1-year MACCE, but not immediately after the procedure.

University and Doctoral School

Semmelweis University, Károly Rácz Doctoral School of Clinical Medicine

Supervisor

-

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

6943

Start

11:35

End

11:40

Authors (legacy)

Peter Tajti, MD, PhD*†, Mohamed Ayoub, MD‡, Abdelkrim Ahres, MD†, Michael Behnes, MD§, Heinz Joachim Buettner, MD*, Prof. Franz-Josef Neumann, MD, PhD*, Kambis Mashayekhi, MD, PD*‖

* Department of Interventional Cardiology, Cardiology and Angiology II, University Heart Center Freiburg – Bad Krozingen, Germany
† Gottsegen György National Cardiovascular Institute – Budapest, Hungary
‡ University Heart and Diabetes Center North-Rhine and Westphalia, Department of Cardiology and Angiology – Bochum, Germany
§ First Department of Medicine, University Medical Center Mannheim – Mannheim, Germany