Mental Health Sciences I.
Baksa, Dániel, PhD
BE9YSR
Department of Pharmacodynamics, Semmelweis University
+36205272302
baksadan@gmail.com
Chronotype Affects Physical and Mental Health Status of Migraineurs
Daniel Baksa1,2,3, Nóra Eszlári1,2, Dóra Török1,2, Gabriella Juhász1,2
1Department of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Budapest, Hungary
2NAP3.0-SE Neuropsychopharmacology Research Group, Hungarian Brain Research Program, Semmelweis University, Budapest, Hungary
3Department of Personality and Clinical Psychology, Institute of Psychology, Faculty of Humanities and Social Sciences, Pazmany Peter Catholic University, Budapest, Hungary
Szóbeli
Mental Health Sciences I.
Hungarian
Mental Sciences
Introduction Previous studies showed mixed results regarding the association between migraine and chronotype.
Aims Our goal was to investigate the effect of chronotype on physical and mental health status of migraineurs and controls in a large cohort.
Methods A sample of the UK Biobank database (Application no. 71718) was used (n=360 112; 54.4% female, mean age: 56.53 years) in our cross-sectional study. Migraine status was based on the G43 ICD-10 code, while chronotype, neuroticism, current depression, stress, body fat percentage (BFP) and overall health rating were measured with self-reported questionnaires. We compared the following groups with ANOVA and Kruskal-Wallis test in SPSS 27: morning type controls (Cm, n=210 787), evening type controls (Ce, n=129 193), morning type migraineurs (Mm, n=12 194) and evening type migraineurs (Me, n=7 938).
Result Morning chronotype was more frequently reported by both migraineurs (60.6%) and controls (62%), however the ratio of evening chronotype among migraineurs was still higher than expected (χ2=16.474, p<0.001). The Me group showed the highest level of neuroticism (F=899.296, p<0.001), current depression (F=1261.6, p<0.001), stress (H=825.4, p<0.001), BFP (F=523.662, p<0.001) and the worst health status (H=2437.492, p<0.001), while the Cm group was in the most advantageous state in every category.
Conclusion Evening chronotype associated with the worst physical and mental health status among migraineurs – suggesting a need for emphasized medical attention in this patient group.
Funding 2017-1.2.1-NKP-2017-00002; NAP2022-I-4/2022; TKP2021-EGA-25; 2019-2.1.7-ERA-NET-2020-00005, ERAPERMED2019-108; K 143391; ÚNKP-22-4-I-SE-10
Semmelweis University, Doctoral School of Mental Health Sciences
Gabriella Juhász
I do not give consent to the publication of my abstract on the website of the congress.
Szabad
elfogadva
szóbeli
nem rendelkezett róla
4105
15:30
15:45
Daniel Baksa1,2,3, Nóra Eszlári1,2, Dóra Török1,2, Gabriella Juhász1,2
1Department of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Budapest, Hungary
2NAP3.0-SE Neuropsychopharmacology Research Group, Hungarian Brain Research Program, Semmelweis University, Budapest, Hungary
3Department of Personality and Clinical Psychology, Institute of Psychology, Faculty of Humanities and Social Sciences, Pazmany Peter Catholic University, Budapest, Hungary