PhD Scientific Days 2023

Clinical Medicine - Posters J

Regional cerebral oxygenation changes during neonatal anesthesia

Előadó neve

Dr. Balog, Vera

Neptun code

JH0A3U

Előadó munkahelye

Department of Pediatrics

Előadó telefonszáma

+36305172247

Előadó e-mail címe

verus.balog@gmail.com

Az előadás címe

Regional cerebral oxygenation changes during neonatal anesthesia

Szerző(k) neve és munkahelye

Vera Balog¹, Sarolta Trinh¹, Magdolna Barra², Balázs Hauser³, Ágnes Jermendy¹
¹Division of Neonatology, Department of Pediatrics,, ²Department of Nuclear Medicine, ³Department of Anesthesiology and Intensive Therapy

Bemutatás módja

Poszter

Szekció

Clinical Medicine - Posters J

Language of the presentation

English

Preferred session

Clinical Medicine

Összefoglaló szövege

Introduction: Neonatal anesthesia is a high-risk procedure with sudden, unpredictable physiological changes occurring in 20-30% of the cases. Cerebral near-infrared spectroscopy (NIRS) may be an important complementary tool to standard monitoring, which can provide early warning signs of impaired tissue oxygenation (rSO2); however, specific absolute rSO2 thresholds are not available to guide management. Current recommendations suggest that rSO2 values decreasing by 20% compared to baseline values may carry an increased risk, but the rate of this scenario is not known in the neonatal population.
Aims: To describe changes in cerebral oxygenation during neonatal non-cardiac surgeries.
Methods: This was a prospective, observational study conducted in the operating room (OR) at the Department of Pediatrics, Semmelweis University. The INVOS 5100C (Medtronic) with neonatal sensors was used for NIRS monitoring. Baseline rSO2 data was defined individually, based on the rSO2 values of the first minute. Mild, moderate, and severe decrease were determined based on the percentage deviation from the baseline value.
Results: Real-time NIRS monitor data was collected from a total of 100 patients, with a median body weight of 2.5 [1.1; 3,0] kg and 31 [6; 68] days postmenstrual age at the time of surgery. The most common types of surgeries were gastrointestinal and thoracic surgeries. The length of NIRS measurements were mean 115 ± 70 minutes. Median baseline NIRS values were recorded based on the values of the first minute. Mild decreases were observed 12 times, with a maximum length of 32 minutes, while severe decrease events were observed 2 times, lasting for a maximum of 195 minutes.
Conclusion: Undesired changes in the rSO2 values were observed frequently during neonatal anesthesia. Sufficient data on the effect of these changes on the outcome is not yet available. The NIRS monitor may be a useful addition to the neonatal monitoring setup in the OR.

Funding: NTP-NFTÖ-22-B-0081, RRF-2.3.1-21-2022-00011,OTKA FK_20 135222, TKP2021-EGA25

University and Doctoral School

Semmelweis University, Károly Rácz Doctoral School of Clinical Medicine

Supervisor

Agnes Jermendy

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

6045

Start

10:48

End

10:53

Authors (legacy)

Vera Balog¹, Sarolta Trinh¹, Magdolna Barra², Balázs Hauser³, Ágnes Jermendy¹
¹Division of Neonatology, Department of Pediatrics,, ²Department of Nuclear Medicine, ³Department of Anesthesiology and Intensive Therapy