PhD Scientific Days 2023

Neurosciences - Posters H

The impact of SARS-CoV-2 infection on the outcome of acute ischemic stroke-A retrospective cohort study

Előadó neve

Dr. Tímea Tünde, Takács

Neptun code

LPLGPA

Előadó munkahelye

Semmelweis University, Department of Neurology

Előadó telefonszáma

06206701432

Előadó e-mail címe

takacsttm@gmail.com

Az előadás címe

The impact of SARS-CoV-2 infection on the outcome of acute ischemic stroke-A retrospective cohort study

Szerző(k) neve és munkahelye

Tímea Tünde Takács 1 2, Ádám József Berki 1 2, Péter Pál Böjti 1 2 3, Rita Stang 1 2, Pablo Antonio Fritz-Reunes 1, Luiz Schnekenberg 4, Timo Siepmann 4 5, Alexandra Pintér 5 6, Szabolcs Szatmári 1 7, Dániel Bereczki 1 7 8, Bence Gunda 1 2
1 Semmelweis University, Department of Neurology, Budapest, Hungary.
2 Semmelweis University, "János Szentágothai" Doctoral School of Neurosciences, Budapest, Hungary.
3National Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary.
4 University Hospital Carl Gustav Carus, Department of Neurology, Dresden, Germany.
5 Division of Health Care Sciences, Center for Clinical Research and Management Education, Dresden International University, Dresden, Germany.
6 Semmelweis University, Department of Family Medicine, Budapest, Hungary.
7 MTA-SE Neuroepidemiological Research Group ELKH, Budapest, Hungary.
8 European Academy of Neurology, EANcore COVID-19 Task Force, Vienna, Austria.

Bemutatás módja

Poszter

Szekció

Neurosciences - Posters H

Language of the presentation

English

Preferred session

Clinical Medicine

Összefoglaló szövege

Acute ischemic stroke (AIS) is a common complication of severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection (COVID-19), but the prognosis of these patients is poorly understood. The aim of our research was to explore the impact of COVID-19 on neurological outcomes in AIS patients. A comparative retrospective cohort study was conducted in 32 consecutive AIS patients with and 51 without COVID-19 between the 1st of March 2020 and 1st of May 2021. The evaluation was based on a detailed chart review for demographic data, medical history, stroke severity, cranial and vessel imaging results, laboratory parameters, COVID-19 severity, hospitalization time, in-hospital mortality, and functional deficits at discharge (modified Rankin Scale, mRS).COVID-19 AIS patients showed tendency to worse initial neurological deficit (NIHSS 9 (3-13) vs. 4 (2-10); p = 0.06), higher rate of large vessel occlusion (LVO; 13/32 vs. 14/51; p = 0.21), had prolonged hospitalization (19.4 ± 17.7 vs. 9.7 ± 7 days; p = 0.003), had lower chance of functional independence (mRS≤2) (12/32 vs. 32/51; p = 0.02) and showed higher in-hospital mortality (10/32 vs. 6/51; p = 0.02). In COVID-19 AIS patients, LVO was more common with COVID-19 pneumonia than without (55.6% vs. 23.1%; p = 0.139).COVID-19-related AIS carries a worse prognosis. COVID-19 with pneumonia seems to be associated with a higher rate of LVO.

University and Doctoral School

Semmelweis University, János Szentágothai Doctoral School of Neurosciences

Supervisor

Dr Bence Gunda

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

6799

Start

11:42

End

11:47

Authors (legacy)

Tímea Tünde Takács 1 2, Ádám József Berki 1 2, Péter Pál Böjti 1 2 3, Rita Stang 1 2, Pablo Antonio Fritz-Reunes 1, Luiz Schnekenberg 4, Timo Siepmann 4 5, Alexandra Pintér 5 6, Szabolcs Szatmári 1 7, Dániel Bereczki 1 7 8, Bence Gunda 1 2
1 Semmelweis University, Department of Neurology, Budapest, Hungary.
2 Semmelweis University, "János Szentágothai" Doctoral School of Neurosciences, Budapest, Hungary.
3National Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary.
4 University Hospital Carl Gustav Carus, Department of Neurology, Dresden, Germany.
5 Division of Health Care Sciences, Center for Clinical Research and Management Education, Dresden International University, Dresden, Germany.
6 Semmelweis University, Department of Family Medicine, Budapest, Hungary.
7 MTA-SE Neuroepidemiological Research Group ELKH, Budapest, Hungary.
8 European Academy of Neurology, EANcore COVID-19 Task Force, Vienna, Austria.