PhD Scientific Days 2024

Mental Health Sciences II.

Dietary Adherence Mediates the Effect of Affective Temperaments on Assisted Reproduction Treatment Success

Előadó neve

Szabó, Georgina, MSc

Neptun code

XFU71J

Előadó munkahelye

SE Doktori Iskola, Mentális Egészségtudományok Tagozat

Előadó telefonszáma

+36203622216

Előadó e-mail címe

szabo.georgina@phd.semmelweis.hu

Az előadás címe

Dietary Adherence Mediates the Effect of Affective Temperaments on Assisted Reproduction Treatment Success

Szerző(k) neve és munkahelye

Georgina Szabó¹, Judit Szigeti F², Miklós Sipos³, Szabolcs Várbíró³, Xénia Gonda⁴

1: Semmelweis University Doctoral School, Faculty of Mental Health Sciences
2: Institute of Behavioral Sciences, Semmelweis University
3: Department of Obstetrics and Gynecology, Semmelweis University
4: Department of Psychiatry and Psychotherapy, Semmelweis University

Bemutatás módja

Szóbeli

Szekció

Mental Health Sciences II.

Language of the presentation

Hungarian

Preferred session

Mental Health Sciences

Összefoglaló szövege

Background: Affective temperaments have been shown to robustly affect infertility treatment success. However, identification of possible mediating factors through which they exert their influence is still lacking. A growing number of results suggest that adherence to recommended treatments may be such a mediator, on the one hand, because affective temperaments are known to influence adherence and on the other hand, because non-adherence negatively influences treatment outcome.
Aim: The aim of this retrospective cohort study was to evaluate whether adherence to physician-prescribed diet and physical activity recommendations mediates the effect of affective temperaments on infertility treatment outcomes.
Methods: Among 308 women who underwent infertility treatment in an Assisted Reproduction Center, affective temperaments, adherence to diet, adherence to physical exercise, and infertility treatment success (clinical pregnancy) were assessed besides detailed medical history and demographic parameters. Associations between affective temperaments, adherence, and assisted reproduction outcomes were analyzed using generalized linear models and causal mediation analysis.
Results: Adherence to physical activity didn’t have an effect, but diet adherence increased the odds of infertility treatment success suggesting its role as a potential mediator. Based on causal mediation analysis, higher depressive and anxious temperament scores were directly associated with a lower likelihood of achieving clinical pregnancy, with effects not mediated by diet adherence; higher irritable temperament scores indirectly decreased the likelihood of achieving clinical pregnancy, mediated by diet adherence; while higher cyclothymic temperament scores decreased the likelihood of achieving clinical pregnancy both directly and indirectly, mediated by diet adherence.
Conclusions: Our results suggest that diet adherence mediates the mechanism by which affective temperaments influence IVF treatment success. Since adherence is a modifiable risk factor of infertility treatment success, screening for affective temperaments may help to identify potentially high-risk non-adherent patient groups and offer patient-tailored treatment, which may help increase the chances of a successful pregnancy and live birth in women undergoing IVF treatment.

University

Semmelweis University

Supervisor

Xénia Gonda, Szabolcs Várbíró

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

szóbeli

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

6928

Start

10:30

End

10:40