PhD Scientific Days 2024

Budapest, 9-10 July 2024

Surgical Medicine

Comparison of anterior column reconstruction techniques after en bloc spondylectomy: a finite element study

Előadó neve

Mr. Pokorni, Agoston Jakab

Neptun code

YEU5AU

Előadó munkahelye

National Center for Spinal Disorders, In Silico Biomechanics Laboratory

Előadó telefonszáma

+36306776269

Előadó e-mail címe

pokorni.agoston@gmail.com

Az előadás címe

Comparison of anterior column reconstruction techniques after en bloc spondylectomy: a finite element study

Szerző(k) neve és munkahelye

Agoston Jakab Pokorni1, Mate Turbucz1, Rita Maria Kiss2, Peter Endre Eltes1,3, Aron Lazary1,3

1: In Silico Biomechanics Laboratory, National Center for Spinal Disorders, Buda Health Center, Budapest
2: Department of Mechatronics, Optics and Mechanical Engineering Informatics, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Budapest
3: Department of Spine Surgery, Department of Orthopaedics, Semmelweis University, Budapest

Bemutatás módja

Szóbeli

Szekció

Surgical Medicine

Language of the presentation

Hungarian

Preferred session

Surgical Medicine

Összefoglaló szövege

Introduction
Total en bloc spondylectomy (TES) effectively treats spinal tumors. The surgery requires a vertebral body replacement (VBR), for which several solutions were developed, whereas the biomechanical differences between these devices still need to be completely understood.
Aims
This study aimed to compare a femur graft (FEM-GRAFT-C), a polyetheretherketone implant (PEEK-IMP-C), a titan mesh cage (MESH-C), and a polymethylmethacrylate replacement (PMMA-C) using a finite element model of the lumbar spine after a TES of L3.
Methods
The models with different VBRs were compared under the same loads. The lower endplate of the L5 vertebra was fixed, while a follower load of 400 N and a moment of 7.5 Nm were applied through the upper endplate of the L1 vertebra to simulate the effect of upper body weight and muscle force in flexion-extension, lateral bending, and axial rotation. The comparison evaluated the rotational stiffness of the structure, the segmental range of motion, and the distribution and maximum of the von Mises stress in the bony endplates of the L2 and L4 vertebrae adjacent to the vertebral replacements.
Result
All models provided adequate initial stability by increasing the rotational stiffness and decreasing the ROM between L2 and L4. The PMMA-C had the highest stiffness for flexion-extension, lateral bending, and axial rotation (215%, 216%, and 170% of intact model), and it had the lowest segmental ROM in the instrumented segment (0.2°,0.5°, and 0.7°, respectively). Maximum endplate stress was similar for PMMA-C and PEEK-IMP-C but lower for both compared to MESH-C across all loading directions.
Conclusion
These results suggest that MESH-C has the highest risk of subsidence and that PMMA-C had similar or better primary spinal stability than other VBRs, which may be related to the larger contact surface and the potential to adapt to the patient’s anatomy.
Funding
This work was supported by the János Bolyai Research Scholarship of the Hungarian Academy of Sciences, by the Hungarian Scientific Research Fund grant Budapest, Hungary (OTKA FK123884), by the New National Excellence Program (ÚNKP-21-5) and by the Doctoral Student Scholarship Program (C1014064) of the Co-operative Doctoral Program of the Ministry of Innovation and Technology, Hungary, financed from the National Research, Development and Innovation Fund.

University

Semmelweis University

Supervisor

Peter Endre Eltes

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

szóbeli

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

7407

Start

14:45

End

14:55