PhD Scientific Days 2024

Poster Session T - Cardiovascular Medicine and Research 3.

Ginger extracellular vesicles caracterisation

Előadó neve

Khamari, Delaram, PhD

Neptun code

3ox2y6

Előadó munkahelye

DGCI- semmelweis university

Előadó telefonszáma

0033632262447

Előadó e-mail címe

dela.kh@outlook.com

Az előadás címe

Ginger extracellular vesicles caracterisation

Szerző(k) neve és munkahelye

Delaram Khamari¹, Ririka Tamura¹, Erdős Bence Gábor¹, Meir Kestecher¹, Panna Királyhidi¹

1: DGCI- semmelweis university

Bemutatás módja

Poszter

Szekció

Poster Session T - Cardiovascular Medicine and Research 3.

Language of the presentation

English

Preferred session

Cardiovascular Medicine and Research

Összefoglaló szövege

Extracellular vesicles (EVs) released universally by cells are of considerable interest because of being potential vectors of the active ingredients in targeted therapies. Some EVs also have a therapeutic effect by themselves without modification. In recent years, plant-derived EVs have been in the center of attention, as they can be produced in a stable, standard and sustainable way. In addition, they are biocompatible and they show a wide range of favourable properties. Ginger root is known to have many beneficial effects. These include among others, anti-inflammatory and anti-carcinogenic effects, and its antioxidant role is also well documented. Several studies attribute a central role to ginger-derived EVs in the effects of ginger.
In the framework of the project, ginger extracellular vesicle-like particles are isolated and characterised by nanoparticle tracking analysis (Zetaview) to determine the size distribution and concentration of these particles. Micro-BCA and SPV Lipid assays are performed to determine the protein and lipid contents, respectively. Also, transmission electron microscopy is carried out to characterize the vesicle-like particles. Ginger root-derived extracellular vesicle-like particles are compared to mammalian counterparts (mammalian extracellular vesicles) in their basic parameters. Finally, experimental systems are set up to investigate the effect of ginger-derived extracellular vesicle-like particles on H9C2 cardiomyocytes.
Finding: ÚNKP-23-1, ÚNKP-23-2, ÚNKP-23-3 és ÚNKP-23-4 Pályázati Adatlap 1. számú mellékle

University

Semmelweis University

Supervisor

Prof Edit Buzas

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

8041

Start

16:05

End

16:08