PhD Scientific Days 2024

Poster Session H - Theoretical and Translational Medicine 1.

Identifying Predictors for the Evolution of Acute Pancreatitis into Recurrent and Chronic Forms: A Systematic Review and Meta-Analysis.

Előadó neve

Dr. Gagyi, Endre Botond

Neptun code

F7RIFK

Előadó munkahelye

Center for Translational Medicine

Előadó telefonszáma

+36308693145

Előadó e-mail címe

endre.gg@gmail.com

Az előadás címe

Identifying Predictors for the Evolution of Acute Pancreatitis into Recurrent and Chronic Forms: A Systematic Review and Meta-Analysis.

Szerző(k) neve és munkahelye

Endre-Botond Gagyi¹

1: Center for Translational Medicine

Bemutatás módja

Poszter

Szekció

Poster Session H - Theoretical and Translational Medicine 1.

Language of the presentation

English

Preferred session

Theoretical and Translational Medicine

Összefoglaló szövege

Introduction: The transition from acute pancreatitis (AP) to recurrent (RAP) and chronic (CP) forms poses significant clinical challenges.
Aim: This systematic review and meta-analysis aimed to identify risk factors associated with this progression.
Methods: Following the protocol registration on PROSPERO (CRD42022368931), we searched Medline, Embase, and Cochrane databases up to December 19th, 2023, for studies examining risk factors for the evolution of AP into RAP or CP. Pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated using the random effects model. Heterogeneity was evaluated using the I² statistic. The risk of bias assessment was performed using the Quality in Prognostic Studies (QUIPS) tool.
Results: A total of 124 articles were included in the meta–analysis, and several risk factors were identified for the progression of AP into RAP and CP. We found the following risk factors of AP recurrence: male gender, smoking, alcoholic etiology, hypertriglyceridemia, diabetes mellitus, pseudocyst, etc. The pooled OR for the male gender was 1.49 (95% CI: 1.31-1.62, I²=25%), for smoking was 1.47 (95% CI: 1.22-1.71, I²=57%), for alcoholic etiology was 1.78 (95% CI: 1.45-2.14, I²=78%), for hypertriglyceridemia was 2.48 (95% CI: 2.16-2.83, I²=9%), for diabetes mellitus was 1.51 (95% CI: 1.21-1.75, I²=0%), for pseudocyst was 2.23 (95% CI: 1.61-3.12, I²=0%). We also found risk factors of RAP progression into CP. The risk of bias was moderate in the majority of the included studies.
Conclusion: These findings suggest that addressing modifiable risk factors might be key in preventing the progression of pancreatitis

University

Semmelweis University

Supervisor

Erőss Bálint

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

7361

Start

15:05

End

15:08