PhD Scientific Days 2024

Cardiovascular Medicine and Research II.

Identification of parameters determining recurrence after atrial fibrillation ablation: Analysis of our three-year follow-up registry

Előadó neve

Dr. Orbán, Gábor

Neptun code

MXHUTJ

Előadó munkahelye

Heart and Vascular Center, Semmelweis University, Budapest, Hungary

Előadó telefonszáma

+36304905897

Előadó e-mail címe

gabor.orban.dr@gmail.com

Az előadás címe

Identification of parameters determining recurrence after atrial fibrillation ablation: Analysis of our three-year follow-up registry

Szerző(k) neve és munkahelye

Gábor Orbán¹, Zoltán Salló¹, Ádám Pál-Jakab¹, István Hizoh¹, Ferenc Komlósi¹, Patrik Tóth¹, Arnold Béla Ferencz¹, Edit Tanai¹, Márton Boga¹, Béla Merkely¹, László Gellér¹, Nándor Szeged¹

1: Heart and Vascular Center, Semmelweis University, Budapest, Hungary

Bemutatás módja

Szóbeli

Szekció

Cardiovascular Medicine and Research II.

Language of the presentation

Hungarian

Preferred session

Cardiovascular Medicine and Research

Összefoglaló szövege

Title: Identification of parameters determining recurrence after atrial fibrillation ablation: Analysis of our three-year follow-up registry

Introduction: Pulmonary vein isolation (PVI) is the most effective treatment for atrial fibrillation (AF). However, the long-term arrhythmia-free success rate varies widely.

Aims: Our study aimed to identify patient-specific and procedural parameters that can be used to predict long-term recurrence-free outcomes of AF ablation more accurately.

Methods: We collected data from patients who underwent PVI between 2010 and 2023. We analyzed the anthropometric data, comorbidities of the patients, as well as the procedural characteristics of the ablations. We also investigated the association of these parameters with recurrence within three years. Our data were evaluated using descriptive statistics, Shapiro-Wilk, Kruskal-Wallis, Dunn post-hoc, and Chi-square tests.

Results: Overall, 2349 patients (median age 63 (56-69) years, 33% female) were included in the study. Of these, 1099 (47%) patients developed AF recurrence during the study period. The median time from ablation to recurrence was 433 (155-981) days. Six hundred and seventeen patients (26%) had AF recurrence in the first year after intervention, 316 patients (14%) between the first and second year, and 166 patients (7%) between the second and third year. Hypertension (73% vs. 67%, p<0.001), valvular disease (4% vs. 3%, p<0.001), non-paroxysmal AF (40% vs. 26%, p<0.001), and AF as the initial rhythm at the beginning of the procedure (55% vs. 37%, p<0.001) were more common in recurrent patients compared to non-recurrent patients. Recurrences were less frequent in patients who were ablated with a steerable sheath (73% vs. 68%, p<0.001) and those who received NOAC therapy (67% vs. 41%, p=0.004).

Conclusion: Hypertension, valvular disease, non-paroxysmal AF, and AF as the initial rhythm at the beginning of the procedure may predict recurrence. In contrast, the use of steerable sheath and NOAC therapy may predict long-term recurrence-free outcomes. We plan to characterize the associations by further statistical analyses.

Funding: ÚNKP-23-3-II-SE-69; MD-PhD Excellence Program: EFOP-3.6.3-VEKOP-16-2017-00009; Gedeon Richter Excellence PhD Scholarship of Gedeon Richter

University

Semmelweis University

Supervisor

Dr. Nándor Szegedi

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

szóbeli

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

6860

Start

15:15

End

15:25