PhD Scientific Days 2024

Poster Session P - Conservative Medicine

2 Year Neurodevelopmental Outcome of Children Born to SARS-CoV-2 Infected Mothers vs. Uninfected Mothers During the COVID-19 Pandemic

Előadó neve

Dr. Pal, Vanda

Neptun code

QVB8TO

Előadó munkahelye

Department of Neonatology, Semmelweis University, Budapest Hungary

Előadó telefonszáma

+36304295404

Előadó e-mail címe

pal.vanda@semmelweis.hu

Az előadás címe

2 Year Neurodevelopmental Outcome of Children Born to SARS-CoV-2 Infected Mothers vs. Uninfected Mothers During the COVID-19 Pandemic

Szerző(k) neve és munkahelye

Vanda Pal¹, Borbala Lukacs MSc², Krisztina Vargane Tari MSc³, Csaba Nador MD¹, Miklos Szabo Prof.¹, Agnes Jermendy MD PhD², Fanni Pekli-Toth MD¹

1: Department of Neonatology, Semmelweis University, Budapest, Hungary
2: Pediatric Center, Semmelweis University, Budapest, Hungary
3: Peto Andras Institute, Semmelweis University, Budapest, Hungary

Bemutatás módja

Poszter

Szekció

Poster Session P - Conservative Medicine

Language of the presentation

English

Preferred session

Conservative Medicine

Összefoglaló szövege

Introduction

Perinatal outcomes are generally favourable in children born to SARS-CoV-2 infected mothers; however less is knokwn about long-term neurodevelopmental outcomes.

Aims

Our aim was to assess the effect of maternal SARS-CoV-2 infection at birth on the outcome of infants at 1 and 2 years of age.

Method

We conducted a case-control study between January 2022 - February 2024 at Semmelweis University, Budapest, Hungary. Term infants born to SARS-CoV-2 positive mothers (COVID-19 group, n=48) and a control group (term infants born to uninfected mothers during the pandemic, n=36) were compared. Neurodevelopmental follow-up visits were completed at 1 and 2 years of age, using the Bayley Scales of Infant and Toddler Development Third Edition (BSID-III).

Results

At 1 year, follow-up rate was 100% in both the COVID-19 and control groups, whereas at 2 years, it was 50% and 64%, respectively. At 1 year of age, children of the COVID-19 group scored lower than the control group on the cognitive (p=0.001) and fine motor skill (p=0.021) subtests of the BSID-III screeening test, however risk stratification for developmental delay was similar in both groups. At 2 years of age, the BSID-III cognitive and motor scale scores were normal (average), or above average in all children of both groups. On the language subtest, 5/24 (20%) children scored below the average in the COVID-19 group, while only 1/23 (4%) in the control group. In accordance, more children of the control group scored in the above-average range (p=0.025).

Conclusion

Children born to SARS-CoV-2 infected mothers scored lower than the control group in some neurodevelopmental areas both at the 1 and 2 year follow-up visits.

Funding
The author(s) received no financial support for the research and authorship.

University

Semmelweis University

Supervisor

Dr. Jermendy Ágnes PhD

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

7976

Start

16:40

End

16:43