PhD Scientific Days 2025

Poster Session II. - U: Cardiovascular Medicine and Research

Effects of Response to Electrical Cardioversion Before Catheter Ablation for Persistent Atrial Fibrillation: a Propensity-Score Matched Analysis

Előadó neve

Dr. Boga Márton

Neptun code

C6A3R0

Előadó munkahelye

Semmelweis University, Heart and Vascular Center

Előadó telefonszáma

+36203325228

Előadó e-mail címe

bogamarton@gmail.com

Az előadás címe

Effects of Response to Electrical Cardioversion Before Catheter Ablation for Persistent Atrial Fibrillation: a Propensity-Score Matched Analysis

Szerző(k) neve és munkahelye

Dr Boga Márton¹, Dr Szegedi Nándor¹

1: Heart and Vascular Center

Bemutatás módja

Poszter

Szekció

Poster Session II. - U: Cardiovascular Medicine and Research

Language of the presentation

English

Preferred session

Cardiovascular Medicine and Research

Összefoglaló szövege

Background: We hypothesize that sinus rhythm maintenance in persistent atrial fibrillation (AF) patients taking antiarrhythmic drugs (AADs) after preprocedural electrical cardioversion (ECV) could predict outcomes after catheter ablation procedures.
Methods: A total of 219 persistent AF patients underwent ECV <6 month before ablation. Patients were categorized into two groups according to their response to ECV: patients in whom SR was restored and maintained until the ablation procedure (ECV-SR group), and patients who have had AF recurrence up to the procedure (ECV-AF group). Then, 1:1 propensity score matching was used to create study groups (94-94 patients). The primary outcomes of the present study were freedom from atrial arrhythmia on/off AADs following a single procedure, and recurrence of persistent AF.
Results: Baseline characteristics were similar, with the only significant difference observed in the frequency of additional ablation beyond pulmonary vein isolation, which was higher in the ECV-AF group (19.1% vs 6.4%, p=0.023). The median follow-up duration was 42 (20–73) month. Freedom from atrial arrhythmia was lower in the ECV-AF group compared to ECV-SR patients (at 36 months: 31.4% vs 51.2%, respectively; crude HR =2.58, 95% CI = 1.58–3.70, p<0.001). The most frequent mode of atrial arrhythmia recurrence was paroxysmal AF in the ECV-SR group and persistent AF in the ECV-AF group. The incidence rate for the recurrence of persistent AF was 7.5/100 patient-years (95% CI=4.5–12.5) in the ECV-SR group and 22.8/100 patient years (95% CI=16.0–32.4) in the ECV-AF group. Freedom from persistent AF at 36 month was 84.3% and 54%, respectively (crude HR=3.72, 95% CI = 1.94–7.14, p<0.001). Differences in the risk of the primary outcomes was similar after multivariable adjustment, and in all analyzed subgroups. The rate of progression to permanent AF was 4.3% in the ECV-SR group and 10.6% in the ECV-AF group over the total follow-up (RR= 2.5, 95% CI =0.86–7.34).
Conclusion: Results from this cohort suggests that response to preprocedural ECV could be a useful indicator for patient selection for catheter ablation of persistent AF.
Funding: New National Excellence Program of the Ministry for Culture and Innovation from the source of the National Research, Development and Innovation Fund (EKÖP-2024-167), SE250+ grant (2024/25).

University

Semmelweis University

Supervisor

Dr Szegedi Nándor

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

phd.section.field

in doctoral studies after complex exam (PhD)

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

8754

Start

18:18

End

18:24