PhD Scientific Days 2025

Poster Session III. - X: Conservative Medicine

Perioperative Homeostasis Changes in Neonates

Előadó neve

Dr. Pal Vanda

Neptun code

QVB8TO

Előadó munkahelye

Semmelweis University Pediatric Center

Előadó telefonszáma

+36304295404

Előadó e-mail címe

pal.vanda@semmelweis.hu

Az előadás címe

Perioperative Homeostasis Changes in Neonates

Szerző(k) neve és munkahelye

Vanda Pal¹, Zsofia Varga², Luca Bogner³, Balazs Hauser⁴, Agnes Jermendy¹

1: Semmelweis University Pediatric Center
2: Semmelweis University Faculty of Medicine
3: Semmelweis University Doctoral College
4: Semmelweis University Department of Anesthesiology

Bemutatás módja

Poszter

Szekció

Poster Session III. - X: Conservative Medicine

Language of the presentation

English

Preferred session

Conservative Medicine

Összefoglaló szövege

Introduction

Maintaining physiological homeostasis in neonates undergoing high-risk procedures requiring anesthesia is crucial. Blood pressure, diuresis and blood gas changes are important markers of homeostatic changes in the perioperative period.

Aims

We aimed to examine perioperative physiological changes in neonates undergoing procedures requiring anesthesia.

Methods

We conducted a prospective observational study between 2021 and 2024 at Semmelweis University Pediatric Center’s Bókay street division on neonates undergoing surgery, weighing less than 6 kgs. We collected our participants’ data retrospectively from hand-written patient charts on diuresis (ml/kg/h), blood gas parameters and mean arterial pressure (MAP) in the pre- and postoperative 6-12 hour periods.

Results

We collected perioperative data on 26 of our 199 study participant. Median [IQR] gestational age was 37 [29-38] weeks, age at the time of surgery was median 2 [2-14] days, average(±SD) body weight was 2515±950 grams. The duration of anesthesia was 146±57 minutes. 50% of the procedures were abdominal, 23% thoracic and 27% were miscallenous. Diuresis was signifinatly lower in the postoperative period (3,6 [2,1-4,9] ml/kg/h before versus 2,5 [1,3-3,6] ml/kg/h after (p=0,022)). There was no significant difference between the pre- and postoperative average and minimum MAP values. Regarding blood gas parameters, we found significantly lower bicarbonate (-1,3 mmol/l, p= 0,49) and base excess (-1,7 mmol/l, p=0,014) levels in the postoperative period.

Conclusion

We found lower diuresis, bicarbonate and base excess levels postoperatively. Further data collection and analysis is needed to determine clinical relevance of this observation.

Funding

Hungarian Scientific Research Fund grants 135222, SE250+ grant

University

Semmelweis University

Supervisor

Agnes Jermendy MD PhD MPH

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

phd.section.field

in doctoral studies before complex exam (PhD)

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

7976

Start

14:36

End

14:42