PhD Scientific Days 2026

Surgical Medicine

Comparison of Triple-bolus and Multi-phase Photon Counting Detector CT protocols in preoperative evaluation of Living Kidney Donor Candidates

Előadó neve

Dr. Csákai-Szőke, Péter

Neptune code

D5E3V3

Előadó munkahelye

Medical Imaging Centre

Előadó telefonszáma

06305437318

Előadó e-mail címe

csakai.szoke.peter@semmelweis.hu

Az előadás címe

Comparison of Triple-bolus and Multi-phase Photon Counting Detector CT protocols in preoperative evaluation of Living Kidney Donor Candidates

Szerző(k) neve és munkahelye

Dr. Csákai-Szőke Péter¹, Dr. Budai Bettina², Dr. Dakhlaoui Hana², Oshriyeh Sina², Hamada Takashi², Dr. Lénárd Zsuzsanna²

1: Semmelweis University Medical Imaging Centre, Heidelberg University Diagnostic and Intervetional Radiology Clinic
2: Medical Imaging Centre

Bemutatás módja

Szóbeli

Szekció

Surgical Medicine

Language of the presentation

English

Preferred session

Surgical Medicine

Összefoglaló szövege

Introduction
Accurate preoperative assessment of renal vascularity in living kidney donor candidates
requires high-quality morphological imaging. As donors are typically healthy and relatively
young, minimizing radiation exposure while maintaining diagnostic accuracy is essential.
Photon-counting detector CT (PCD-CT) offers higher spatial resolution, improved image
quality, and reduced radiation and contrast agent doses compared with conventional
Energy-integrating detector CT (EID-CT) systems. However, data on its use in living kidney
donor evaluation are lacking.

Aims
In this study, we aimed to compare two widely accepted CT protocols for donor assessment
– the multiphase protocol and the triple-bolus protocol – using PCD-CT.

Methods
A total of 40 consecutive living kidney donor candidates from Semmelweis University were
included in this study. 20 donor candidates underwent triple-bolus PCD-CT (non-contrast
and combined angiographic-venous-delayed), while 20 donor candidates underwent
conventional four-phase PCD-CT (non-contrast, angiographic, venous and delayed) scans.
Both CTA and triple-bolus scan had a reconstruction slice thickness of 0.4 mm. Ionizing
radiation effective dose (ED) and iodine-based contrast agent dose were recorded for both
protocols. Image quality was assessed using contrast-to-noise ratio (CNR) and signal-tonoise ratio (SNR).

Result
Age, weight, and BMI were comparable between the two PCD-CT groups. In PCD-CT triple
bolus study the average ED was 55% lower, in comparison to that of PCD-CT four-phase
protocol (6.34±1.57 mSv vs 14.1±4.4 mSv, respectively, p < 0.001), while iodine-based
contrast agent dose was significantly higher (0.57±0.09 vs. 0.31±0.03 g iodine/kg, p<0.001).Image quality was similar, with no significant differences in CNR (p=0.436) or SNR (p=0.327)
across the PCD-CT protocols.

Conclusion
A triple-bolus PCD-CT technique optimized for renal assessment enables high-quality
preoperative imaging with substantially reduced radiation exposure in living kidney donor
candidates. Despite its triple-bolus injection protocol, the iodine dose substantially remains
lower than that of standard single-bolus multiphase EID-CT protocols (~0.8–1.2 g/kg).

Funding
No funding was received.

University

Semmelweis University

Supervisor

Dr. Lénárd Zsuzsanna

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

phd.section.field

in doctoral studies before complex exam (PhD)

Kind

Szabad

Status

elfogadva

Accepted presentation method

szóbeli

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

9099

Start

16:15

End

16:25