PhD Scientific Days 2026

Poster Session 2.Q - Cardiovascular Medicine and Research

Image quality assessment of high concentration contrast agents 400 mg I/mL compared to 370 mg I/mL and 350 mg I/mL in ultra-high resolution coronary CT angiography using photon-counting detector CT

Előadó neve

Dr. Csulak, István

Neptune code

I82F14

Előadó munkahelye

Semmelweis University Medical Imaging Centre

Előadó telefonszáma

+36308782863

Előadó e-mail címe

csulak.istvan@semmelweis.hu

Az előadás címe

Image quality assessment of high concentration contrast agents 400 mg I/mL compared to 370 mg I/mL and 350 mg I/mL in ultra-high resolution coronary CT angiography using photon-counting detector CT

Szerző(k) neve és munkahelye

István Csulak¹, Lili Száraz¹, Attila Fülöp², Fanni Kovács³, Sámuel Beke¹, Barnabás Baksa¹, Dalma Tóth³, Kristóf Nagy¹, Réka Sebestyén-Dósa¹, Melinda Boussoussu⁴, Borbála Vattay⁴, Milán Vecsey-Nagy⁴, Akos Varga-Szemes⁵, Filippo Cademartiri⁶, Bálint Szilveszter⁴, Pál Maurovich-Horvat¹

1: Department of Radiology, Medical Imaging Centre, Semmelweis University, Budapest, Hungary
2: Faculty of Medicine, Medical Informatics, Heidelberg University, Heidelberg, Germany
3: Faculty of Medicine, Semmelweis University, Budapest, Hungary
4: Heart and Vascular Center, Semmelweis University, Budapest, Hungary
5: Department of Radiology and Radiological Science, Medical University of South Carolina SC, Charleston, USA
6: IRCCS SYNLAB SDN, Naples, Italy

Bemutatás módja

Poszter

Szekció

Poster Session 2.Q - Cardiovascular Medicine and Research

Language of the presentation

Hungarian

Preferred session

Cardiovascular Medicine and Research

Összefoglaló szövege

Introduction: Photon-counting detector CT (PCD-CT) enables ultra-high resolution (UHR) coronary imaging, however image quality (IQ) remains influenced by iodine concentration.

Aims: We compared three contrast agents 400-370-350 mg I/mL, respectively to determine optimal choice for UHR coronary CT angiography (CCTA).

Method: 123 patients scanned with UHR CCTA were analyzed. Matched groups were formed. Intraluminal attenuation, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and image noise (IN) were calculated. Diagnostic confidence was scored.

Results: Three contrast agents were evenly distributed among patients (n=41 each) with similar baseline characteristics and flow rates (5.0±0.3 ml/s; p=0.81). 400 mg I/mL had significantly higher intraluminal attenuation in distal coronary arteries (525.8±109.0 HU) compared to 350 mg I/mL (487.7±186.3 HU) and 370 mg I/mL (428.5±107.9 HU; p<0.05). No significant differences were found in SNR (8.1±2.0 vs. 7.6±1.8 vs. 7.4±1.8; p=0.2358), CNR (9.2±2.2 vs. 9.0±2.1 vs. 8.9±2.1; p=0.7855), or IN (63.4±13.2 vs. 64.2±16.4 vs. 61.9±18.0; p=0.7624). 400 mg I/mL provided higher attenuation at distal segment level and improved diagnostic confidence.

Conclusions: 400 mg I/mL is superior to lower iodine concentration contrast media for UHR coronary stenosis assessment. Results support prioritizing 400 mg I/mL for UHR coronary imaging using PCD-CT.

Funding: Supported under the SE250+ PhD Scholarship of Semmelweis University

University

Semmelweis University

Supervisor

Prof. Pál Maurovich-Horvat

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

phd.section.field

in doctoral studies before complex exam (PhD)

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

9758

Start

19:00

End

19:03