PhD Scientific Days 2026

Poster Session 2.Q - Cardiovascular Medicine and Research

CCTA-Derived PCAT Metrics in Heart Transplant Patients With Accelerated CAV

Előadó neve

Dr. Boussoussou, Melinda, PhD

Neptune code

IMK4SC

Előadó munkahelye

Semmelweis University Heart and Vascular Center

Előadó telefonszáma

06206632859

Előadó e-mail címe

melinda.b.md@gmail.com

Az előadás címe

CCTA-Derived PCAT Metrics in Heart Transplant Patients With Accelerated CAV

Szerző(k) neve és munkahelye

Melinda Boussoussou¹, Dániel Novák¹, Barbara Sipos¹, Borbála Vattay¹, Zsófia Jokkel¹, Dávid Asztalos¹, Milán Vecsey-Nagy¹, Andrea Bartikowsky¹, Bálint Szilveszter¹, Béla Merkely¹, Ádám Jermendy¹

1: Semmelweis University Heart and Vascular Center

Bemutatás módja

Poszter

Szekció

Poster Session 2.Q - Cardiovascular Medicine and Research

Language of the presentation

English

Preferred session

Cardiovascular Medicine and Research

Összefoglaló szövege

Introduction: Cardiac allograft vasculopathy (CAV) is a leading cause of long-term mortality in heart transplant recipients. Coronary CT angiography enables non-invasive surveillance, and pericoronary adipose tissue (PCAT) metrics have emerged as markers of coronary inflammation.
Aim: Our aim was to assess longitudinal changes in PCAT characteristics during rapid progression of CAV, a context in which their behavior remains poorly understood.
Methods: We retrospectively analyzed 32 heart transplant recipients (mean age 55.2 years; 12.5% female) undergoing serial CCTA. Inclusion required new ≥50% stenosis in a major coronary branch consistent with CAV. PCAT parameters along the right coronary artery were assessed at diagnosis (CT2) and prior scan (CT1) using Autoplaque. Changes were analyzed with linear regression.
Results: PCAT gradient significantly increased between CT1 and CT2 (+16.3; p<0.001). PCAT attenuation showed a small decrease (−2.7 HU; p=0.028), while PCAT volume remained unchanged (p=0.92).
Conclusions: Rapid CAV progression is characterized by a marked rise in PCAT gradient, with minimal changes in attenuation and no change in volume. PCAT gradient may serve as a sensitive non-invasive marker of pericoronary inflammation in heart transplant recipients.

University

Semmelweis University

Supervisor

Ádám Jermendy

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

phd.section.field

after finishing doctoral studies with absolutorium (PhD)

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

4775

Start

19:18

End

19:21