PhD Scientific Days 2026

Poster Session 3.R - Cardiovascular Medicine and Research

Multimodal Wearable Telemetry and Ambulatory Monitoring of Cardiovascular Autonomic Changes During Short Duration Space Mission

Előadó neve

Dr. Nagy-Bozsoky, József

Neptune code

S8P73T

Előadó munkahelye

Department of Aviation and Space Medicine

Előadó telefonszáma

+36709533359

Előadó e-mail címe

nagy.jozsef@stud.semmelweis.hu

Az előadás címe

Multimodal Wearable Telemetry and Ambulatory Monitoring of Cardiovascular Autonomic Changes During Short Duration Space Mission

Szerző(k) neve és munkahelye

Dr. József Nagy-Bozsoky¹, Dr. Maya Baksay¹, Lilla Gréczi¹, Dr. Klaudia Vivien Nagy¹, Prof. Dr. Béla Merkely¹

1: Department of Aviation and Space Medicine

Bemutatás módja

Poszter

Szekció

Poster Session 3.R - Cardiovascular Medicine and Research

Language of the presentation

English

Preferred session

Cardiovascular Medicine and Research

Összefoglaló szövege

Introduction and Aims: Short-duration spaceflight induces rapid cardiovascular adaptation, yet high-resolution 24-hour autonomic and vascular data remain limited. We evaluated whether a multimodal wearable device combined with ambulatory blood pressure monitoring (ABPM) can detect hemodynamic and autonomic adaptation during an 18-day mission on the Internation Space Station.

Methods: A longitudinal within-subject design with ground-based control was implemented. Continuous 24-hour ECG and photoplethysmography were recorded using a wearable smart garment; oscillometric ABPM recorded blood pressure and pulse wave velocity (PWV). Sessions occurred pre-flight (L-29, -24, -9), in-flight (L+4, L+10), and post-flight (R+1, R+4). Time-varying HRV was analyzed via time-domain (RMSSD), frequency-domain (LF, HF, LF/HF), and non-linear indices (DFA alpha 1, deceleration/acceleration capacity). Linear mixed-effects modeling compared phase-related changes relative to control.

Results: PWV declined during daytime (6.1±0.37 to 5.7±0.34 m/s) and night (5.7±0.29 to 5.4±0.38 m/s; p=0.027), with no significant changes in systolic or diastolic BP. HRV analysis showed reduced mean HR (day: 72.8±2.6 to 58.3±3.7 bpm; night: 60.9±3.1 to 49.1±1.3 bpm; p=0.045) and increased RMSSD (day: 31.5±2.6 to 35.4±5.8 ms; night: 36.7±7.2 to 41±13.4 ms; p=0.045). LF power decreased (day: 89.5 ±1.6n.u. to 78.7 ±1.82n.u.; night: 86.8 ±1.6n.u. to 77.3 ±0.1n.u.; p=0.014), HF increased (day: 12.3 ±7.25n.u. to 23.7 ±10.4n.u.; night: 16 ±6.4n.u. to 26.7 ±15.05n.u.; p=0.01), and LF/HF decreased (p<0.001). Deceleration capacity increased (p=0.045), and acceleration capacity was reduced (p=0.045). Autonomic indices confirmed increased parasympathetic activity (day: -0.7±0.2 vs. 0.3±0.5; night: 0.12±0.4 vs. 1.4±0.3; p=0.01). No significant changes persisted post-flight.

Conclusion: Integrated 24-hour monitoring revealed coordinated autonomic and hemodynamic adaptation characterized by parasympathetic predominance and reduced arterial stiffness consistent with cephalad fluid shift. The study demonstrates the feasibility of continuous, non-invasive cardiovascular telemetry for operational spaceflight missions.

Funding: This work was supported by the Hungarian Astronaut (HUNOR) Program through the HUN-REN Támogatott Kutatócsoportok Irodája.

University

Semmelweis University

Supervisor

Dr. Klaudia Vivien Nagy

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

phd.section.field

in doctoral studies before complex exam (PhD)

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

9109

Start

14:00

End

14:03