PhD Scientific Days 2026

Poster Session 2.Q - Cardiovascular Medicine and Research

Cardiac Magnetic Resonance Evaluation of Structural Heart Disease in a Large Athlete Cohort

Előadó neve

Dr. Balla, Dorottya

Neptune code

TIAEVR

Előadó munkahelye

Heart and Vascular Centre, Semmelweis University

Előadó telefonszáma

+36301794501

Előadó e-mail címe

balla.dorottya07@gmail.com

Az előadás címe

Cardiac Magnetic Resonance Evaluation of Structural Heart Disease in a Large Athlete Cohort

Szerző(k) neve és munkahelye

Dr. Dorottya Balla¹, Dr. Szabó Liliána¹, Dr. Dohy Zsófia¹, Dr. Drobni Zsófia¹, Dr. Vincze Viktória¹, Dr. Meskó Csongor¹, Dr. Kovács Árpád¹, Dr. Sydó Nóra¹, Dr. Csulak Emese¹, Dr. Kiss Orsolya¹, Prof. Dr. Bödör Csaba², Dr. Suhai Ferenc¹, Dr. Tóth Attila¹, Prof. Dr. Merkely Béla¹, Prof. Dr. Vágó Hajnalka¹

1: Heart and Vascular Centre, Semmelweis University
2: Department of Pathology and Experimental Cancer Research, Semmelweis University

Bemutatás módja

Poszter

Szekció

Poster Session 2.Q - Cardiovascular Medicine and Research

Language of the presentation

English

Preferred session

Cardiovascular Medicine and Research

Összefoglaló szövege

Introduction: Sudden cardiac death (SCD) in young athletes is most commonly related to underlying structural myocardial disorders. Cardiac magnetic resonance imaging (CMR) has emerged as a key diagnostic modality for detailed myocardial tissue characterization and for identifying substrates associated with malignant ventricular arrhythmias.
Aims: To assess the prevalence and spectrum of structural myocardial diseases detected by CMR in athletes and to evaluate the underlying etiologies associated with SCD and life-threatening ventricular arrhythmias.
Methods: Athletes performing ≥6 hours of weekly training who were referred to our center for CMR due to suspected structural heart disease were included. Genetic testing was performed in athletes with confirmed myocardial disease or documented malignant ventricular arrhythmias.
Results: A total of 857 athletes (752 males; mean age 25.3±11.3 years) underwent CMR evaluation. Structural myocardial abnormalities were identified in 142 athletes (115 males; mean age 30.2±12.6 years; weekly training volume 12.3±6.5 hours). Among cardiomyopathies, hypertrophic cardiomyopathy (HCM) was diagnosed in 42 athletes, arrhythmogenic cardiomyopathy (AC) in 16, and dilated cardiomyopathy (DCM) in 12 cases. Non-ischemic myocardial fibrosis or scarring was detected in 52 athletes, including patterns consistent with acute or previous myocarditis and atypical fibrosis. Among athletes evaluated following resuscitation or sustained ventricular tachycardia, structural abnormalities were identified in 17 individuals, including AC (8 cases), HCM (1 case), mitral annular disjunction (1 case), ischemic injury (2 cases), and atypical fibrosis (5 cases). Genetic testing was performed in 53 athletes, revealing pathogenic or likely pathogenic variants in 14 cases and variants of uncertain significance in 25 cases.
Conclusions: In this large athlete cohort, HCM was the most frequent cardiomyopathy, while AC was the predominant substrate associated with SCD. Beyond classical cardiomyopathies, atypical non-ischaemic myocardial scar represents a relevant structural finding in athletes undergoing CMR and may constitute an important arrhythmogenic substrate.

University

Semmelweis University

Supervisor

Prof. Dr. Vágó Hajnalka

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

phd.section.field

in doctoral studies after complex exam (PhD)

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

7475

Start

18:30

End

18:33