PhD Scientific Days 2026

Poster Session 1.O - Dental Research

Risk Factors for the Emergence of Multidrug-resistant Bacteria in Patients with Head and Neck Infections

Előadó neve

Dr. Kiss, Dorottya

Neptune code

J4IUAB

Előadó munkahelye

Department of Oro-Maxillofacial Surgery and Stomatology

Előadó telefonszáma

06302085500

Előadó e-mail címe

kiss.dorottya@hotmail.com

Az előadás címe

Risk Factors for the Emergence of Multidrug-resistant Bacteria in Patients with Head and Neck Infections

Szerző(k) neve és munkahelye

Dorottya Kiss¹

1: Department of Oro-Maxillofacial Surgery and Stomatology

Bemutatás módja

Poszter

Szekció

Poster Session 1.O - Dental Research

Language of the presentation

English

Preferred session

Dental Research

Összefoglaló szövege

Introduction: The emergence and spread of multidrug-resistant (MDR) pathogens have been linked to excessive antibiotic use, as well as patient-related factors such as hospitalization.
Aims: This study investigated the clinical determinants of antimicrobial resistance (AMR) and the occurrence of MDR bacteria.
Methods: We evaluated 4492 bacterial isolates from 1719 patients and analyzed the association between resistance levels and various patient-related factors, including age, primary diagnosis, comorbidities, oral hygiene, smoking, alcohol use, and prior antibiotic therapy. AMR rate was graded from 0 to 3, and a mixed-effect continuation ratio was used for the analysis.
Results: Patients with oral cancer (OR 1.38, 95% CI 1.06–1.80), a history of smoking (OR 1.19, 95% CI 1.01–1.41), immunosuppressive therapy (OR 1.36, 95% CI 1.06–1.75), insulin-treated diabetes (OR 1.57, 95% CI 1.05–2.35), or cardiovascular disease (OR 1.28, 95% CI 1.02–1.61) had significantly higher risk of infection with MDR bacteria. Prior antibiotic use (OR 1.44, 95% CI 1.24–1.68), older age (OR 1.01, 95% CI 1.00–1.01), and female sex (OR 1.28, 95% CI 1.09–1.49) were also significantly associated with progression to multidrug resistance.
Conclusions: These findings suggest that, beyond selective pressure from antibiotics, individual patient characteristics may also contribute to the development of MDR bacteria in head and neck infections and. Clinicians should consider these factors during hospitalization, particularly regarding infection prevention and the responsible selection of antibiotics.
Funding: This work was supported by the 2024-2.1.2-eköp-kdp-2024-00002 university research scholarship program of the ministry for culture and innovation from the source of the national research, development and innovation fund.

University

Semmelweis University

Supervisor

Prof. Dr. Katalin Kristóf, Prof. Dr. Árpád Joób-Fancsaly

Publication of my abstract

I do not give consent to the publication of my abstract on the website of the congress.

phd.section.field

in doctoral studies after complex exam (PhD)

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

9043

Start

17:00

End

17:03