PhD Scientific Days 2026

Poster Session 2.K - Mental Health Sciences

Psychological Intervention Improves Quality of Life, but Survival in Patients with Early-Stage Cancer: a Systematic Review and Meta-analysis of randomized clinical trials

Előadó neve

Bognár, Sára Anna, MSc

Neptune code

CJI77H

Előadó munkahelye

Center for Translational Medicine

Előadó telefonszáma

06302725500

Előadó e-mail címe

bognar.sara@gmail.com

Az előadás címe

Psychological Intervention Improves Quality of Life, but Survival in Patients with Early-Stage Cancer: a Systematic Review and Meta-analysis of randomized clinical trials

Szerző(k) neve és munkahelye

Sára Anna Bognár, MSc¹

1: Center for Translational Medicine

Bemutatás módja

Poszter

Szekció

Poster Session 2.K - Mental Health Sciences

Language of the presentation

English

Preferred session

Mental Health Sciences

Összefoglaló szövege

Introduction
The effectiveness of psychological interventions (PI) for malignant diseases remains controversial, particularly regarding their impact on survival and quality of life (QoL) in cancer patients.
Aims
We aimed to investigate the effect of psychological interventions on survival outcomes and quality of life in patients with cancer.
Method
A systematic search of MEDLINE, Cochrane, and Embase databases was conducted to identify randomized controlled trials comparing psychological interventions to standard care (PROSPERO registration number: CRD42021282327).
Outcomes included overall survival (OS), recurrence-free survival (RFS), and multiple domains of quality of life.
Subgroup analyses were performed based on: provider, type of intervention, environment, duration of intervention, cancer stage, cancer type. Pooled hazard ratios (HR) and standardized mean differences (SMD) with 95% confidence intervals (CI) were calculated using a random-effects model.
Results: Pooled hazard ratios (HR) and standardized mean difference (SMD) with 95% confidence intervals (CI) were calculated using a random-effects model. The OS and RFS did not differ significantly between the two groups (OS:HR = 0.97; CI 0.87–1.08; RFS:HR = 0.99; CI 0.84–1.16). However, there was significant improvement in the intervention group in all the analyzed domains of QoL; in the global (SMD = 0.65; CI 0.35–0.94), emotional (SMD = 0.64; CI 0.33–0.95), social (SMD = 0.32; CI 0.13–0.51) and physical (SMD = 0.33; CI 0.05–0.60) domains. The effect of PI on QoL was generally positive immediately, 12 and 24 weeks after intervention, but the effect decreased over time and was no longer found significant at 48 weeks. The results were better in the breast cancer group and early stages of cancer.
Conclusion: PIs do not prolong survival, but they significantly improve the QoL of cancer patients. PI should be added as standard of care 3–4 times a year, at least for patients with early-stage cancer.
Funding: Supported by the Semmelweis University Research, Development and Innovation Fund.

University

Semmelweis University

Supervisor

Prof Hegyi Péter and Dr Katalin Márta

Publication of my abstract

I give consent to the publication of my abstract on the website of the congress.

phd.section.field

after finishing doctoral studies with absolutorium (PhD)

Kind

Szabad

Status

elfogadva

Accepted presentation method

poszter

Előadás fájl jóváhagyás

nem rendelkezett róla

Előadó

9839

Start

18:12

End

18:15