PhD Scientific Days 2018

Budapest, 19-20 April 2018

Abstracts by authors

Bence Ágg
Increased Visceral Arterial Tortuosity in Marfan Syndrome: A Possible New Approach to Risk Stratification.

Isameddin Aghrbi
Study on the dissolution improvement of a poorly water soluble model drug using wet milling technique

Donát Alpár
Rapid and comprehensive screening for DNA copy number abnormalities in plasma cell myeloma using a next-generation sequencing based approach

Nóra Angyal
Genetic association analysis of the canonical Wnt-signaling receptor genes LRP5 and LRP6 with Attention Deficit Hyperactivity Disorder

Petra Aradi
Characterizing the role of lymphatics in autoimmune arthritis

Mikaela Aresti
SODIUM BICARBONATE AND CHLORINE DIOXIDE AS EFFECTIVE BIOCIDES AGAINST DENTAL BIOFILM

Imre Barabás
Computer assisted decision making in cardiac surgery: from 3D preoperative planning to computational fluid dynamics in the design of surgical procedures

Máté Baradits
EEG microstate features based classification: Schizophrenia vs. Healthy Control

Marcell Baranyi
Antitumor effects of the novel lipophilic bisphosphonate BPH1222 in in vitro and in vivo colorectal cancer models

Bianka Barna
Connection of Suicidal Behavior Disorder And Substance Abuse Disorder

Dóra Batta
The concept of an integrated central pressure-stiffness score, a potential new tool for cardiovascular risk stratification: First results in chronic kidney disease

Dóra Becsei
Cognitive functions in children with Phenylketonuria

Márta Békés
EFFECT OF XENOSENSORS ON THE DIFFERENTIATION OF IMMUNE CELLS

László Bíró
Endocannabinoid interactions in the regulation of behavioural responses to trauma

Dóra Bogdán
Structure elucidation of squalenoylated ecdysteroid derivatives by NMR spectroscopy

Péter Bogyi
Complications after MICRA and conventional transvenous VVI pacemaker implantation; long term follow-up

Péter Pál Böjti
Relationship between patent foramen ovale and cryptogenic stroke in a retrospective hospital-based study

Enikő Bóna
Predictors of orthorexia nervosa in a sample of fitness enthusiasts and exploration of "clean eating" practices

Kriszta Katinka Boros
Malnutrition as a risk factor to impaired vaccine response in paediatric inflammatory bowel disease

Alexandra Czigola
Effects of substrate, ceramic thickness, translucency and cement shade on the color of CAD/CAM lithium-disilicate crowns

László Czumbel
Machined versus Sand-blasted Endosseous Dental Implants – Meta Analysis

Lea Danics
Antitumor Effects of Modulated Electro-hyperthermia in Triple-negative Breast Cancer Bearing Mice

Ábel Decmann
MicroRNA expression profiling in benign and malignant adrenal tumors

Arianna Dégi
VALIDATION OF SURFACE DISTANCE MEASUREMENT BY MRI FOR PULSE WAVE VELOCITY DETERMINATION

Tamás Demeter
Investigation of salivary flow and oral health status in Hungarian smokers and non-smokers

Katalin Déri
The assesment of the dental effects of a tooth-bone-borne expansion appliance

Adrienn Dobai
Comparison of conventional lateral cephalogram and CBCT-based cephalometry using different projections for adaptation of cephalometric norms.

Zsófia Dohy
Fragmented QRS in hypertrophic cardiomyopathy – myocardial scar marker?

Viktória Doma
Alteration of mutant allele frequency is significant in visceral metastases of melanoma

Zsófia Drobni D.
Genetic components of coronary plaque composition and plaque volume: a classical twin study

Andrea Édes
Perception of pain is influenced by rumination: an fMRI study

Nóra Eszlári
Effect of GABRA6 gene on suicide risk is dependent on stress

János Fekete
ROC plotter: An Online Biomarker Validation Tool using Cancer Gene Expression Data and ROC analysis

Szabolcs Fekete
Risk factors of reoffending in psychiatric patients who underwent involuntary treatment

Zsuzsanna Fodor
Beta event related spectral perturbation as a potential biomarker in MCI: preliminary results

Mohammadhassan Foroughbakhshfasaei
A comparative enantioseparation of thalidomide class of drugs using polysaccharide-type stationary phases in lights of elution sequence and thermodynamic analysis in polar organic mode

Kinga Fülöpné Németh
Application of next generation sequencing for mitochondrial genome analysis in pituitary adenomas

Orsolya Galamb
LINC00152 long non-coding RNA promotes the proliferation of SW480 colon carcinoma cells through regulation of cell cycle and WNT signaling pathway

Bernadett Gánti
Reproducibility of gingival thickness measurement by PIROP ultrasonic biometer

Edina Gradvohl
A systemic change in CPR training for lay – skill teaching by peer education

Gyula Gyebnár
Single patients as outliers in neuroimaging? Introducing the Mahalanobis-distance for epileptic lesion detection using DTI data

Gábor Hajdú
Benzaldehyde-induced specific adaptive cellular stress and detoxification responses in C. elegans

Levente Herman
Screening for anti-NMDAR antibodies in the serum of patients with first episode psychosis

Krisztina Horváth
BEHAVIORAL CHANGES OF INTERLEUKIN 6 DEFICIENT MICE

Beáta Hriczóné Dr. Szebeni
ROLE OF NANOVESICLES IN THE DEVELOPMENT OF PERITONEAL FIBROSIS DURING PERITONEAL DIALYSIS

Zoltán Hujber
IDH1 mutation is associated with higher cellular respiration and decreased glutamine oxidation in glioma cells

Géza Jakab
Formulation and Investigation of Baicalin in Self-emulsifying Drug Delivery Systems

Gellért Levente Joós-Kovács
Laboratory Scanner Method - Accuracy of Indirect CAD/CAM digitalization

Fanni Juhász
Comparison of bone maturation staging methods

Dávid Juriga
Synthesis and investigation of biodegradable poly(amino acid) based nano drug-delivery systems

Brigitta Kakuszi
Social cognition in Attention Deficit Hyperactivity Disorder: An Event Related Potential Study

Alexandra Kalmár
Whole transcriptome analysis reveals colorectal cancer-associated long non-coding RNAs including UCA1 already dysregulated in colorectal adenomas

Máté Kapitány-Fövény
The explanatory role of socio-cultural factors in cross-national variability of mental disorders’ prevalence

Orsolya Kapuy
The systems biological study of cellular life-and-death decision in neurodegenerative diseases

Dorottya Virág Kardos
HypACT Inject Auto device – an easy, fast and sterile method to produce the best quality platelet rich fibrin membrane

Tamás Kaucsár
Functional investigation of miR-17-5p inhibition in kidney ischemia-reperfusion injury in mice

Dávid Keresztes
Identification of predictive serum biomarkers for chemotherapy resistence in prostate cancer using mass spectrometric proteome analysis

Tália Magdolna Keszthelyi
Identification of a novel gene in a patient with polycystic kidney, cerebral atrophy and truncus arteriosus

Richárd Kiss
Dissection of Clonal Evolution By Temporal Mutation Profiling in Chronic Lymphocytic Leukemia Patients Treated with Ibrutinib

Zoltán Kiss
Biobank for analysis of the effects of biological therapy on the microbiome in pediatric patients with inflammatory bowel disease

Éva Kocsmár
Tissue-based in situ detection of the clarithromycin resistance for the personalized Helicobacter pylori eradication therapy

Ildikó Kocsmár
Degree of chromosomal abnormalities detected by UroVysion test from urine-voided bladder cancer cells (UVyScore) is able to predict muscle invasion of bladder cancer

Kinga Viktória Kőhalmi
Genetic biomarkers and clinical significance of erythema marginatum in Hungarian patients with hereditary angioedema due to C1-inhibitor deficiency

Orsolya Kolodzey-Angeli
Semi-manual retinal vessel density analysis on optical coherence tomography angiography images of healthy adults

Márton Kolossváry
Computed Tomography Radiomics Can Identify Invasive and Nuclear Imaging Markers of Plaque Vulnerability

Réka Koren
Emotionally Focused Couple Therapy Training Effects on Therapists: A Bilingual and Tri-National Comparison

Anna Kosyreva
Relationship of the resistance to hypoxia with the severity of systemic inflammatory response induced by a high-dose of lipopolysaccharide in male Wistar rats of different age groups

Árpád Ferenc Kovács
Status of redox homeostasis at cellular and extracellular vesicle levels in preeclamptic pregnancies

Attila Kovács
Genetic determination of myocardial mechanics: towards a deeper understanding of heart failure with preserved ejection fraction?

Annamária Kövesdi
The presence of GEP-NET tumors in young patients is a good predictor for MEN1 gene mutation

Petra Kövy
TGFβ1 GENE POLIMORPHISM INFLUENCE THE OUTCOME OF HEMATOPOIETIC STEM CELL TRANSPLANTATION

Ildikó Krencz
mTORC2 as a potential therapeutic target in renal cell carcinoma of kidney transplant recipients

Dániel Kulin
Digital health in the general practice – results from a pilot study

Szandra László
BEHAVIOURAL TRAINING FOR SLEEP PROBLEMS IN WILLIAMS SYNDROME

Szilvia László
Long-term selective inhibition of cyclooxygenase-2 by rofecoxib does not cause small intestinal dysbiosis in the rat

Zsófia Lázár
COPD EXACERBATIONS WITH INCREASED BLOOD EOSINOPHIL PERCENTAGE ARE ASSOCIATED WITH LESS SYSTEMIC INFLAMMATION AND BETTER LUNG FUNCTION IMPROVEMENT

Milán Leindler
Modern 3D graphic softwares in investigating body image disturbance

András Hugó Lékó
Identification of differentially expressed genes in the preoptic area of mother rats

Anna Lengyel
Genotype-phenotype correlations of a peculiar chromosomal abnormality

Miklós Lengyel
The cloxyquin (5-chloroquinolin-8-ol) derivative A2764 is a selective and state dependent inhibitor of TRESK background K+ channel

Nikolett Lupsa
Functional characterization of peptidase inhibitor 16 (PI16), a novel marker of skin homing CD8+ cytotoxic T cells.

Stefani Maihoub
Differentiation between normal vestibular system and central vestibular dysfunctions.

János Major
Abdominal pain-related functional gastrointestinal disorders among Hungarian adolescents

Márton Margita
The NRF2-mediated oxidative stress’s influence to the process of cell cycle

Éva Margittai
The subcellular localization of GLUT10 and its role in the pathomechanism of arterial tortuosity syndrome

Csilla Marosi
Perception in schizophrenia: an ERP-study

Bernadett Martinecz
The molecular anatomy of microglia-neuron interactions and their role in regulation of neuronal activity

Zsuzsanna Mihály
CAROTID PLAQUE COMPOSITION IS A PROGNOSTIC FACTOR OF CEREBRAL ISCHAEMIA IN PATIENTS WITH CAROTID ARTERY STENOSIS .

Ágnes Mikó
Identification of incompletely penetrant variants by a population genetic approach

Mohd Yaqub Mir
Gal-1 Expression Profile in rat central nervous system derived cell cultures

Arashi Mirzahosseini
Physico-chemical characterization of brain metabolites using multinuclear magnetic resonance techniques

Júlia Moldvai
Oral health related quality of life for patients undergoing physical medicine and rehabilitation

Emese Molnár
The Effectivity of Novel Mesenchymal Stem Cell Therapy in Graft-Versus-Host Disease

István Molnár
Investigation of pH inducated calcium ion patterns

Kristóf Molnár
A new model for the evaluation of the mechanical properties of sutured implants

Ákos Nádasdi
Can the adiponutrin (PNPLA3) rs738409 genotype influence the metabolic activity of non-alcoholic fatty liver disease?

Ádám Nagy
Uncovering new potential target genes in Acute Myeloid Leukemia

Zsófia Nagy
One Year Incidence of Iatrogenic Atrial Septal Defect after Radiofrequency or Cryoballoon Ablation for Paroxysmal Atrial Fibrillation

Balázs Németh
Pharmacological stimulation of the NO/SGC/cGMP pathway reduces ischemia-reperfusion injury and improves donor organ function in a rat model of heterotopic heart transplantation

Kinga Nyíri
DEVELOPMENT OF IN VITRO INHIBITOR TESTING METHODS FOR ONCOGENIC MUTANT KRAS PROTEIN TARGET

Attila Oláh
Electrophysiologic investigation of exercise-induced cardiac hypertrophy in a rodent model of athlete’s heart

Zsófia Ónodi
Efficient isolation of extracellular vesicles from blood plasma based on iodixanol density gradient ultracentrifugation and bind-elute chromatography

Zoltán Orgován
Computer aided design of new selective inhibitors against KRAS G12C

Viktor Óriás
Evaluation of Digital Variance Angiography in carotid and cerebral X‐ray angiography

Éva Pál
Vitamin D deficiency impairs geometrical structure and vascular reactivity of rat cerebral arterioles

Gyula Pálfy
Understanding the role of dynamics in function of oncogenic KRas mutants

Zsófia Edit Pápay
FORMULATION AND CHARACTERIZATION OF NOVEL APIGENIN LOADED BIOCOMPATIBLE PARTICLES WITH VISCOELASTIC PROPERTIES

Anikó Papp
Sleep disturbance and epilepsy in a women with possible Posterior Cortical Atrophy

Zsuzsanna Katalin Papp
Parent-child agreement on health related quality of life in a Hungarian pediatric sample

Irina Pató
Impulsivity and observed stress, as a risk factor of the probability of suicide in law enforcement institutes

Pál Perge
Analysis of blood-borne exosomal microRNAs in benign and malignant adrenocortical tumors

Gábor Petővári
The in vitro effects of mTOR and metabolic inhibitors in human glioma cells

Peter Petschner
The magnitude of the effect of various risk SNPs is a function of stress exposure in depression – a comparison with 5-HTTLPR

Domonkos Pinke
Novel long-term 3D imaging method for recording neuronal activity and plasticity by acusto-optical microscopy

Éva Pinti
Identification of a rare DSD

Lőrinc Sándor Pongor
Analysis of expression alteration causing mutations in breast cancer

Jaikumpun Pongsiri
BICARBONATE INHIBITS THE GROWTH OF CYSTIC FIBROSIS-RELATED BACTERIA IN ARTIFICIAL SPUTUM MEDIUM

Ekaterina Postovalova
LYMPHOCYTE SUBPOPULATIONS IN THE PERIPHERAL BLOOD AND COLON IN EXPERIMENTAL CHRONIC ULCERATIVE COLITIS

Frigyes Sámuel Rácz
Multifractal dynamics of resting-state functional connectivity in the prefrontal cortex

Tamás Radovits
Characterization of the dynamic changes in left ventricular morphology and function induced by exercise training and detraining

Lilla Reiniger
COMPARISON OF HOMOLOGOUS RECOMBINATION DEFICIENCY IN BREAST CARCINOMAS AND CORRESPONDING BRAIN METASTASES.

Tímea Rengeiné Kiss
The impact of individualized hemostasis management on the King’s college Therapeutic Intervention Scoring System (King’s-TISS)

Andrea Reszegi
Decorin delivery hinders primary and metastatic tumor formation in the liver

Nima Kakhki Rezvani
Metabolic profiling of human melanoma cells with high and low metastatic capacity

Dominika Rittler
Therapeutic sensitivity and in vivo tumorigenicity of a novel effusion derived BRAF mutant anaplastic thyroid cancer cell line

Mihály Ruppert
Pressure-volume analysis reveals characteristic gender differences in cardiac function in a rat model of aortic banding-induced myocardial hypertrophy

Andrea Rzepiel
Circulating microRNAs as potential biomarkers of pediatric acute lymphoblastic leukemia

Wuttapon Sadaeng
Gamma-aminobutyric acid for preventing postherpetic neuralgia after herpes zoster infection– A systematic review and meta-analysis

Imre Sallai
Developing a novel diagnostic method in periprosthetic joint infection by detecting neutrophil derived microvesicles in synovial fluid

Konrád Sántha
Evaluation of excipients and processing agents intended for the compression of pellets into tablets

Norbert Zétény Sárga
Employee performance appraisal systems in Hungarian hospitals

Balázs Sarkadi
Analytical performance of next generation sequencing based methods in molecular genetic diagnosis of pheochromocytoma/paraganglioma.

Fanni Sebák
Role and structure of scaffolds in canonical serine protease inhibitor variants: an NMR spectroscopic view

Eszter Simoncsics
Own pain experience and avoidance of health care providers and its impact on their attitudes towards patient care

Anna Sólyomváry
Investigation of fruit components in the fruit of Cirsium erisithales

Agnes Sudy
The Negative Impact of Social Jetlag on Sleep Quality and Cardiac Control During Sleep

Dániel Sugár
THE ACTIVATION OF THE LOCAL SKIN RENIN–ANGIOTENSIN SYSTEM FOLLOWING DIETARY SALT OVERLOAD

Csaba Sumánszki
Thyroid function of adult Hungarian patients with Phenylketonuria: a cross-sectional analysis

Cecília Surján
Short to mid-term mortality of hip fracture patients in Hungary – what influences the rates?

Gergely Sváb
Modeling the citric acid cycle, malate-aspartate and citrate-pyruvate shuttles

Katalin Sviatkó
Pavlovian conditioning on the wheel

Bernadett Svraka
Prevalence of mathematical anxiety

Nóra Sydó
Field testing follow-up in soccer team of young athletes

Eszter Szabó
HIGH-RESOLUTION STRUCTURE OF THE D444V DISEASE-CAUSING MUTANT OF HUMAN DIHYDROLIPOAMIDE DEHYDROGENASE

Evelin Szabó
Dyadic Coping in Romantic Relationships: A Personal Project Approach

Tamás Dömötör Szalai
Complex modeling of parental attachment, patient's personality and eating disorder symptoms

Szabolcs Szatmári
Cutaneous Autonomic Pilomotor Testing to Unveil the Role of Neuropathy Progression in Early Parkinson's Disease

Balázs Szécsényi-Nagy
The avail of hospital care in the last 5 years of patient lives

Zsuzsanna Szél
Perceived stress and mental health conditions among minority students in medical universities in Hungary

Anita Szőke
RAS-mediated Pathways in the Metabolic Regulation of the Circadian Clock

András Szőnyi
Brainstem nucleus incertus controls contextual memory formation

Angéla Takács
In vitro measurements of the influences in the effect of bortezomib upon antioxidant co-treatments on myeloma and melanoma cell lines

Rozália Takács
The frequency of catatonic syndrome in an acute psychiatric ward

Vanda Téglási
Characteristics of spreading and vascularization of human brain metastases

Bálint Tél
Increased chance of acute pancreatitis in patients with inflammatory bowel disease – a meta-analysis

Sang-ngoen Thanyaporn
Effect of orally administrated probiotics on Porphyromonas gingivalis in oral cavity: review and meta-analysis

Anna Mária Tőkés
Prognostic significance of tumor-infiltrating lymphocytes in breast carcinomas

Gergely Toldi
Immune cell subsets, cytokine and cortisol levels during the first week of life in neonates born to preeclamptic mothers

Zoltán János Tolnai
SELECTION OF NT-PROBNP SPECIFIC APTAMERS

Bibiána Török
Epigenetic aspects of vasopressin-deficient Brattleboro rats’ schizophrenia-like behavior

Marianna Török
Gender differences on the adatptation of coronary resistance arteries in sport

András Dávid Tóth
Identification of blood pressure regulating compounds using a novel, high-throughput screening-compatible ligand binding assay

Balázs Tóth
Comparison of biophysical behaviors provides insight into the evolution of TRPM2 channels from simple multicellular organisms to man

Estilla Zsófia Tóth
Biocompatibility of the SU-8 in the central nervous system

Gergő Tóth
Physicochemical characterization and cyclodextrin complexation of tyrosine kinase inhibitors

Zsombor Tóth-Vajna
Screening of peripheral arterial disease in primary health care, special attention to patients in murky zone

Ivan Tsvetkov
Morphological changes of testis and subpopulations of lymphocytes in blood of C57BL/6 mice with supraphysiological testosterone concentration

Péter Ujma
Individual slow wave morphology is a marker of ageing

Kinga Katalin Vajda
Challenges and opportunities for elderly people’s day care services in the light of growing and changing needs

Máté Vajda
Synthesis of novel 6-oxomorphinan derived pyrazolo- and isoxazolomorphinans: Potential compounds with mixed opioid receptor binding profile.

Luca Valkó
FACTORS AFFECTING QUALITY OF LIFE DURING HOME MECHANICAL VENTILATION

Borbála Vánkos
The prognostic value of p16 expression in Hungarian oral squamous cell carcinoma patients

Anna Varga
Efficacy of iFightDepression online self-help tool in mild forms of depression

Dániel Végh
Oral health complications and diabetes

Blanka Vékony
The appearance of fashion diets in case of dog holders and their pets

Apor Veres-Székely
Involvement of Parkinson’s disease 7 in inflammatory bowel diseases: relation to interleukin-17 and tumor necrosis factor-alpha

Ágnes Vincze
Patient adherence: can we trust the physicians’ evaluation?

István Vincze
Investigation of D-serine transport in SH-SY5Y cell line and cortical astrocytes

Laura Vizkeleti
GENETIC PATTERNS OF BRAIN METASTASIZATION IN LUNG CANCER USING NGS TECHNOLOGY

Xing Wang
FOOD MEDICINE - TRADITIONAL CHINESE MEDICINE- PREVENTION

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LEFT VENTRICULAR REVERSE REMODELING AFTER TRANSCATHETER AORTIC VALVE IMPLANTATION IS ASSOCIATED WITH HYPO-ATTENUATED LEAFLET THICKENING

Zoltán Zádori
Analysing the long-term effect of cyclooxygenase-2 inhibition on small intestinal mucosal integrity and microbiota

Éva Zsák
WAYS OF REMEMBERING IN PERINATAL LOSS – APPROACHES AND TENDENCIES IN HUNGARIAN AND ITALIAN INSTITUTIONS

Ekaterina Zvorykina
NON-CENTROSOMAL MICROTUBULES PLAY A MAJOR ROLE IN FORMATION OF MICROTUBULE ARRAY IN FIBROBLAST-LIKE CELLS